Publications by authors named "Gulcin Bas"
Study Design: Prospective biochemical study of comparison of A Disintegrin and Metalloproteinase with Thrombospondin motifs-4 (ADAMTS-4) and A Disintegrin and Metalloproteinase with Thrombospondin motifs 5 (ADAMTS5) levels in preoperative and postoperative venous blood, as well as in disc tissue obtained during surgery, in patients undergoing surgery for intervertebral disc disease, with enzyme levels in venous blood from a control group.
Objective: To compare the levels of ADAMTS-4 and ADAMTS-5 between patients with degenerative intervertebral discs and a healthy control group, aiming to identify biomarkers associated with intervertebral disc degeneration.
Literature: Although numerous studies have investigated the relationship between ADAMTS-4 and ADAMTS-5 enzymes and degeneration in experimental rat models and human tissues, no study has correlated their serum levels with intervertebral disc degeneration.
Objective: Epilepsy negatively affects the social functioning of patients. Epilepsy surgery is a treatment with superior rates of seizure freedom. The psychosocial outcomes after epilepsy surgery depend on several factors, including the patient's coping style.
View Article and Find Full Text PDFObjectives: Pseudotumor cerebri syndrome (PTC) is a chronic disorder, which is initially treated by conservative measures, yet surgery is inevitable in case of progressive worsening of vision or headache despite medical treatment. The surgical management is controversial including CSF diversion procedures and optic decompression. The purpose of this study was to evaluate the efficacy of different surgeries in PTC and to present surgical outcomes in a single center.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated how diffusion tensor tractography (DTT) helps in planning surgeries for patients with spinal intramedullary tumors and its effect on their neurological outcomes.
- Researchers reviewed data from patients who had DTT between 2019 and 2022, examining tumor types, surgical decisions, and neurological status pre- and post-surgery using the McCormick scale.
- Results showed that DTT effectively categorized tumors, with Type 1 being fully resectable, and it aided in determining which patients were suitable for surgery, leading to positive postoperative neurological outcomes.
Case report: Spinal drop metastasis of IDH-mutant, 1p/19q-codeleted oligodendroglioma.
Front Neurol
December 2022
Background: Symptomatic spinal metastases of oligodendroglioma are rare. Moreover, none of the previously published cases demonstrated the typical IDH mutation and 1p/19q-codeletion for this glial tumor. This case presents an IDH mutant, 1p/19q-codeleted oligodendroglioma with multiple spinal drop metastases.
View Article and Find Full Text PDFBackground: To assess the efficacy of postoperative antibiotics on postoperative infection in clean supratentorial craniotomies.
Methods: This study is a prospective, randomized, single-blind, and placebo-controlled clinical trial that included consecutive patients who underwent clean supratentorial craniotomy between November 2017 and September 2020 and evaluated the effectiveness of postoperative antibiotic prophylaxis on postoperative infection.
Results: A total of 80 patients were included and the whole group was divided into two groups.