Publications by authors named "Gui-Ying Zhao"
High-altitude hypoxia provides a natural laboratory for studying adaptation in plateau mammals. As an interface for oxygen and nutrient exchange, placenta plays a critical role in fetal development. While high-altitude adaptation in systemic physiological responses and cardiopulmonary tissues has been well-studied, a comprehensive landscape of porcine placental transcriptomic diversity and alternative splicing (AS) complexity across altitudes remains lacking.
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- Triple-negative breast cancer (TNBC) is particularly aggressive and currently lacks effective targeted treatments, prompting research into potential therapies like Isobavachalcone (IBC).
- IBC, derived from Psoralea corylifolia L., has been identified as a natural inhibitor of the SIRT2 enzyme, demonstrating significant anticancer effects through in vitro and in vivo studies.
- The compound works by stabilizing SIRT2, disrupting key cellular interactions, and activating pathways that lead to reduced tumor growth and enhanced apoptosis, presenting IBC as a promising candidate for future drug development against TNBC.
[Study on the growth, development and artificial propagation of Hypericum ascyron].
Zhong Yao Cai
June 2011
Objective: To explore the morphological changes, growth conditions and artificial propagation of Hypericum ascyron.
Methods: The morphological changes were observed and recorded in the scene, the height and diameter of the plants were measured; the growth Verhaulst model was set up with the SPSS 17.0 software; the sexual reproduction and asexual reproduction were carried out in artificial cultivation.