Publications by authors named "Guang-Hui Pan"
Background: 25-hydroxyvitamin D is the body's main storage form of vitamin D and is internationally recognized as the best indicator of vitamin D status in the human body. There is a scarcity of research investigating the interrelationship between serum 25-hydroxyvitamin D (25(OH)D) levels and mortality among elderly individuals with hyperlipidemia. To address this knowledge gap, we examined the association between serum 25(OH)D levels and mortality in an older hyperlipidemic population from NHANES, while controlling for other influential factors.
View Article and Find Full Text PDFHeidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy.
Front Pharmacol
September 2022
Renal fibrosis is a common pathway for the progression of various chronic kidney diseases (CKD), and the formation and deterioration will eventually lead to end-stage renal failure, which brings a heavy medical burden to the world. HeidihuangWan (HDHW) is a herbal formulation with stable and reliable clinical efficacy in the treatment of renal fibrosis. However, the mechanism of HDHW in treating renal fibrosis is not clear.
View Article and Find Full Text PDFArticle Synopsis
- Calcineurin inhibitors like tacrolimus are essential for organ transplants but can harm kidney function, impacting long-term survival post-transplant.
- A pilot study tested low-dose tacrolimus combined with mesenchymal stem cells (MSCs) on 16 kidney transplant patients, comparing it to a standard tacrolimus dosage in another 16 patients.
- Results showed that patients receiving the low-dose and MSCs had stable kidney function and similar outcomes at 24 months, suggesting that MSCs allow for safer, lower doses of calcineurin inhibitors without additional toxicity.
[The safety analysis of living-related kidney donors in short term after transplantation].
Zhonghua Wai Ke Za Zhi
September 2009
Objective: To evaluate the safety of living related donors in short term after transplantation.
Methods: Two hundred and fifty-one cases of living related donor kidney transplantation from May 2000 to July 2007 were analysed retrospectively. There were 117 male and 134 female aged from 22 to 72 years old, with a mean of 46.