Publications by authors named "Gopalakrishnan Saroja Seethapathy"

The resin of Canarium strictum Roxb. is used for rheumatism and asthma; the bark is used as a mosquito repellent. The major compounds in the resin are triterpenoids, but as no studies have been performed on the bark, this study investigated this economically important resource.

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Article Synopsis
  • The increasing commercialization of Ayurveda products has led to heightened adulteration and substitution issues, fueled by supply constraints and fraudulent practices in the herbal market.
  • Despite the use of DNA metabarcoding to assess the authenticity of 79 Ayurvedic herbal products, results showed a low ingredient fidelity, with only 67% for single ingredient products and just 21% for multiple ingredients.
  • The study underscores the need for better quality control in herbal products and the potential of DNA metabarcoding as an authentication tool, while stressing the importance of standardizing this method for regulatory use.
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Article Synopsis
  • Garcinia L. fruits are known for their high (-)-hydroxycitric acid content, which is linked to weight loss and anti-obesity benefits.
  • The study utilized DNA barcoding to confirm the authenticity of Garcinia samples in Indian herbal markets, revealing that G. gummi-gutta and G. indica were predominant with no adulteration found.
  • NMR analysis showed varied levels of (-)-hydroxycitric acid in both raw and supplement forms, emphasizing the inconsistency in the amounts present across different products.
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Ethnopharmacological Relevance: More than 15,000 angiosperm species are dioecious, i.e., having distinct male and female individual plants.

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Medicinal plants such as Cassia, Senna, and Chamaecrista (belonging to the family Fabaceae) are well known for their laxative properties. They are extensively used within indigenous health care systems in India and several other countries. India exports over 5000 metric tonnes per year of these specific herbal products, and the demand for natural health product market is growing at approximately 10-15% annually.

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To authenticate Ayurvedic medicinal plants Ativisha (Aconitum heterophyllum) and Musta (Cyperus rotundus) at the raw drug source and in prepared herbal products, nrDNA ITS sequence based SCAR markers were designed and validated spp.-specific SCAR primers gave amplicon of 415 bp and 134 bp, respectively, in authentic species. The SCAR primers (Cyr-FP and Cyr-RP) could identify tissue sample containing 750 μg to 4.

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