Design of plant-based bigels by incorporating candelilla wax oleogel and xanthan gum hydrogel for oral curcumin delivery.

This study evaluated the role of plant-based biphasic gel (bigel) formulations prepared using various ratios of xanthan gum (XG) hydrogel and Candelilla wax-based oleogel for the delayed release of curcumin (CUR). Microscopic studies revealed that the bigel exhibited a bicontinuous phase distribution. FTIR analysis suggested increased hydrogen bonding with a higher proportion of hydrogel in the bigel formulations.

Nitrodopamine modified MnO NS-MoSQDs hybrid nanocomposite for the extracellular and intracellular detection of glutathione.

We have developed a highly sensitive and reliable fluorescence resonance energy transfer (FRET) probe using nitro-dopamine (ND) and dopamine (DA) coated MnO nanosheet (ND@MnO NS and DA@MnO NS) as an energy acceptor and MoS quantum dots (QDs) as an energy donor. By employing surface-modified MnO NS, we can effectively reduce the fluorescence intensity of MoS QDs through FRET. It can reduce MnO NS to Mn and facilitate the fluorescence recovery of the MoS QDs.

Preparation and Characterization of Novel Oleogels Using Jasmine Floral Wax and Wheat Germ Oil for Oral Delivery of Curcumin.

Oleogels (OGs) have gained a lot of interest as a delivery system for a variety of pharmaceuticals. The current study explains the development of jasmine floral wax (JFW) and wheat germ oil (WGO)-based OGs for oral drug (curcumin) delivery application. The OGs were made by dissolving JFW in WGO at 70 °C and cooling it to room temperature (25 °C).