Changes in the caries-associated microbiota and caries experience in children and adolescents with type 1 diabetes: A systematic review and meta-analysis.

Objective: This systematic review aimed to determine the differences in the caries-associated microbiota and caries experience among children with type 1 diabetes (T1D) compared to healthy children in observational studies.

Design: Registered in PROPSERO (CRD42024529842), this review involved searching four electronic databases (PubMed, Embase, Scopus and Web of Science) from inception to April 2024. Citation searching was further performed on eligible studies from the database search.

Environmentally Relevant Concentrations of Triphenyl Phosphate (TPhP) Impact Development in Zebrafish.

A common flame-retardant and plasticizer, triphenyl phosphate (TPhP) is an aryl phosphate ester found in many aquatic environments at nM concentrations. Yet, most studies interrogating its toxicity have used µM concentrations. In this study, we used the model organism zebrafish () to uncover the developmental impact of nM exposures to TPhP at the phenotypic and molecular levels.

Molar-root incisor malformation - a systematic review of case reports and case series.

Objectives: Molar-root incisor malformation (MRIM) is a seldom reported condition characterised by disturbances in root development of first permanent molars. This systematic review aimed to collate the clinical characteristics of individuals diagnosed with MRIM.

Materials And Methods: A systematic search strategy using PubMed, Embase, Web of Science, and SCOPUS databases was performed through to March 2023.

Establishing a Mouse Model for Sexual Transmission and Male Reproductive Tract Persistence of Ebola Virus.

Ebola virus disease (EVD) has resulted in the death of over 15 000 people since its discovery in 1976. At least 1 incident of re-emergence of EVD has been associated with persistent male reproductive tract infection in a patient surviving EVD greater than 500 days prior. To date, animal models of Ebola virus (EBOV) infection have failed to fully characterize the pathogenesis of reproductive tract infection.

Toxicity with proton therapy for oral and/or oropharyngeal cancers: A scoping review.

Background: Oral and/or oropharyngeal cancers account for approximately 2% of all malignancies, with variation across age groups, genders, and geographic locations. Treatments for oral and/or oropharyngeal cancers usually consist of a combination of surgical excision most commonly followed by radiotherapy ± chemotherapy and/or immunotherapy/biotherapy depending on the nature of the malignancy. The significant morbidity caused by high-dose radiotherapy to the head and neck region is widely observed.

Prevalence and morphological features of molar-root incisor malformation in children attending a specialist paediatric dental unit.

Background: Molar-root incisor malformation (MRIM) is a rare dental anomaly featuring constricted cervical margins and tapered, narrow root and pulp morphology, often associated with severe toothache and infection.

Aim: The aim of this study was to determine the prevalence of MRIM in children seen in a specialist paediatric dental unit of a tertiary referral hospital and to describe the characteristics of affected individuals.

Design: This study was an audit of children attending from November 2020 to November 2021.

Type 1 diabetes, periodontal health, and a familial history of hyperlipidaemia is associated with oral microbiota in children: a cross-sectional study.

Background: Hyperlipidaemia may play a significant role in the interrelationship between type 1 diabetes (T1D) and periodontal disease. A potential mechanism that links these three aspects together is the oral microbiota. We wanted to determine if there is an association between hyperlipidaemia, periodontal disease, and the oral microbiota of children with T1D, as this has not yet been explored.