Top Curr Chem (Cham)
August 2025
Gases are integral to Earth's climate and ecosystem balance, but human activity has significantly altered atmospheric composition by increasing greenhouse gas emissions. In 2025, carbon dioxide emissions were estimated at around 39-41 billion tons, reflecting a continued increase. Emissions of carbon monoxide, sulfur dioxide, and nitrogen dioxide were expected to remain close to 2.
View Article and Find Full Text PDFThis study highlights the transformation of lignin, an agricultural byproduct, into a multifunctional material with significant environmental applications. A chromium-doped zinc oxide/lignin nanocomposite (L@CrZnO) was synthesized and characterized to evaluate its dual functionality in organic pollutant removal and antibacterial activity. Methylene blue (MB) was used as a model contaminant to assess photocatalytic performance under varying conditions of dosage (0.
View Article and Find Full Text PDFIntroduction: Rheumatic heart disease (RHD) results from chronic inflammation and fibrosis of heart valves following untreated rheumatic fever, yet its immunopathology, particularly involving T helper 17 (Th17) cells and their cytokines, is not fully understood. Th17 cells are prominent drivers of inflammation and have been linked to various autoimmune diseases, suggesting their potential role in RHD-related valve damage. This study examines Th17-associated cytokines-interleukin (IL)-17, IL-6, IL-23, and IL-21-in RHD.
View Article and Find Full Text PDFHepatitis C virus (HCV) infection is a major global health burden, with an estimated 58 million people chronically infected worldwide, according to the World Health Organization (WHO). While many people remain asymptomatic during the early stages of infection, chronic hepatitis C can cause long-term liver damage, significantly increasing the morbidity and mortality associated with the disease. The primary objective of this technical report is to find the efficacy of novel antiviral therapies in treating hepatitis C in a tertiary care hospital in Lahore.
View Article and Find Full Text PDFObjective: To determine the short- and medium-term cardiac outcomes in children admitted with multisystem inflammatory syndrome in children at a tertiary care centre in Pakistan.
Methods: Children fulfilling the criteria for multisystem inflammatory syndrome and admitted to the hospital between April 2020 and March 2022 were enrolled in this prospective longitudinal cohort study. From admission to discharge, laboratory and cardiac parameters were recorded for all patients, who were subsequently followed up in clinics at various intervals.
Background: Knowledge about multisystem inflammatory syndrome in children (MIS-C) is evolving, and evidence-based standardised diagnostic and management protocols are lacking. Our review aims to summarise the clinical and diagnostic features, management strategies and outcomes of MIS-C and evaluate the variances in disease parameters and outcomes between high-income countries (HIC) and middle-income countries (MIC).
Methods: We searched four databases from December 2019 to March 2023.
J Pak Med Assoc
April 2024
To discuss the use of T3™, a data aggregation, visualization, and risk analytic platform in a single centre and its framework for implementation of such a tool in clinical care. We share experience of a tool implemented in a tertiary care Intensive Care Unit (ICU) with limited resources. Superusers were identified and trained.
View Article and Find Full Text PDFObjective: To assess the prevalence of shoulder pain and functional disability (SPFD) in Type-1 diabetic patients, and to explore its association with duration of the disease, age and gender.
Methods: A cross-sectional survey was carried out on previously diagnosed patients with Type-1 diabetes mellitus between April 2019 and March 2020. Data was collected from six hospitals including three tertiary care hospitals of Islamabad and Rawalpindi.
Human activity recognition (HAR) aims to recognize the actions of the human body through a series of observations and environmental conditions. The analysis of human activities has drawn the attention of the research community in the last two decades due to its widespread applications, diverse nature of activities, and recording infrastructure. Lately, one of the most challenging applications in this framework is to recognize the human body actions using unobtrusive wearable motion sensors.
View Article and Find Full Text PDFHypertension is an antecedent to cardiac disorders. According to the World Health Organization (WHO), the number of people affected with hypertension will reach around 1.56 billion by 2025.
View Article and Find Full Text PDFPak J Med Sci
January 2020
Objective: To assess the frequency of wrist pain in students due to mobile phone usage, and impact of usage hours and screen size of mobile phones on pain and disability at wrist joint.
Methods: A cross-sectional survey was conducted among students studying in different universities of Islamabad and Rawalpindi belonging to both public and private sectors. The study was conducted between May 2018 and March 2019.