The Behavioral Impact of the Massachusetts Flavored Tobacco Products Ban on Cigarette Smoking Among Adults Aged ≥21 Years.

Introduction: In June of 2020, Massachusetts became the first state to implement a statewide ban on flavored tobacco. To date, no study has analyzed the behavioral outcomes of a comprehensive statewide ban on flavored tobacco products among representative state samples of adults aged ≥21 years.

Methods: Using a difference-in-difference model from repeated cross-sectional data (Behavioral Risk Factor Surveillance System), the authors compared cigarette smoking prevalence in Massachusetts before (January 2017-May 2020) with that after (June 2020-December 2022) the implementation of a flavor ban, with 35 states serving as a comparison.

Multivariate genome-wide association study of sleep health demonstrates unity and diversity.

There has been a recent push to focus sleep research less on disordered sleep and more on the dimensional sleep health. Sleep health incorporates several dimensions of sleep: chronotype, efficiency, daytime alertness, duration, regularity, and satisfaction with sleep. A previous study demonstrated sleep health domains correlate only moderately with each other at the genomic level (|rGs| = 0.

A Review of the Effects of Adolescent Cannabis Use on Physical Health.

The current review highlights the available research related to cannabis and indicators of physical health in a variety of domains. Various studies have found associations between cannabis use with pulmonary, cardiovascular, gastrointestinal, and endocrine function as well as body mass index and sleep. At this time, more research is needed to understand the influence of cannabis use on physical health, particularly among adolescent samples.

Sleep Health at the Genomic Level: Six Distinct Factors and Their Relationships With Psychopathology.

Background: Poor sleep is associated with many negative health outcomes, including multiple dimensions of psychopathology. In the past decade, sleep researchers have advocated for focusing on the concept of sleep health as a modifiable health behavior to mitigate or prevent these outcomes. Sleep health dimensions often include sleep efficiency, duration, satisfaction, regularity, timing, and daytime alertness.

Novel Methods of Cannabis Use and Lower Sleep Duration Among High School Students.

Background: The general use of cannabis in adolescence is associated with various sleep deficits. While traditional smoking remains the most common form of cannabis consumption amongst adolescents, novel methods of administration are becoming more popular and available due to legalization. The association of these novel methods of use with sleep in adolescence has yet to be studied and research is needed to inform public health initiatives.

A Review of the Effects of Adolescent Cannabis Use on Physical Health.

The current review highlights the available research related to cannabis and indicators of physical health in a variety of domains. Various studies have found associations between cannabis use with pulmonary, cardiovascular, gastrointestinal, and endocrine function as well as body mass index and sleep. At this time, more research is needed to understand the influence of cannabis use on physical health, particularly among adolescent samples.

Cannabinoid Exposure and Subjective Effects of THC and CBD in Edible Cannabis Products.

The popularity of edible cannabis products continues to grow in states with legal cannabis access, but few studies have investigated the acute effects of these commercially available products. The present study sought to explore the effects of three commercially available edible products with different levels of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). A sample of regular cannabis users (=99) were evaluated.

Characterisation of the genetic relationship between the domains of sleep and circadian-related behaviours with substance use phenotypes.

Sleep problems and substance use frequently co-occur. While substance use can result in specific sleep deficits, genetic pleiotropy could explain part of the relationship between sleep and substance use and use disorders. Here we use the largest publicly available genome-wide summary statistics of substance use behaviours (N = 79,729-632,802) and sleep/activity phenotypes to date (N = 85,502-449,734) to (1) assess the genetic overlap between substance use behaviours and both sleep and circadian-related activity measures, (2) estimate clusters from genetic correlations and (3) test processes of causality versus genetic pleiotropy.

Genetic Liability to Cannabis Use Disorder and COVID-19 Hospitalization.

Background: Vulnerability to COVID-19 hospitalization has been linked to behavioral risk factors, including combustible psychoactive substance use (e.g., tobacco smoking).

Genetic Liability to Cannabis Use Disorder and COVID-19 Hospitalization.

Behavioral and life style factors plausibly play a role in likelihood of being hospitalized for COVID-19. Genetic vulnerability to hospitalization after SARS-CoV2 infection may partially relate to comorbid behavioral risk factors, especially the use of combustible psychoactive substances. Paralleling the COVID-19 crisis has been increasingly permissive laws for recreational cannabis use.

The structure and subtypes of gambling activities: Genetic, psychiatric and behavioral etiologies of gambling frequency.

The multitude of gambling activities has given rise to heterogeneous ways of analyzing these behaviors and may partially underlie the lack of replication in gambling research. The current study used complementary analyses to investigate the structure, typology and etiology of gambling behaviors in a discovery sample of 2,116 twins (54.86% female; M = 24.

Cannabis use and sleep: Expectations, outcomes, and the role of age.

Study Objectives: Determine relationship between cannabis use with 1) expectations of cannabis being a sleep aid, 2) subjective sleep outcomes, and 3) the influence of age on these relationships.

Methods: In 152 moderate cannabis users with a wide age range (67% female, mean age = 31.45, SD = 12.

Sleep deficits and cannabis use behaviors: an analysis of shared genetics using linkage disequilibrium score regression and polygenic risk prediction.

Study Objectives: Estimate the genetic relationship of cannabis use with sleep deficits and an eveningness chronotype.

Methods: We used linkage disequilibrium score regression (LDSC) to analyze genetic correlations between sleep deficits and cannabis use behaviors. Secondly, we generated sleep deficit polygenic risk score (PRS) and estimated their ability to predict cannabis use behaviors using linear and logistic regression.

Prenatal cannabis exposure and sleep outcomes in children 9-10 years of age in the adolescent brain cognitive development study.

Objectives: Analyze the associations between prenatal cannabis exposure and child sleep outcomes.

Methods: Data from the Adolescent Brain Cognitive Development Study (ABCD Study®) was used to determine whether maternal reports of prenatal cannabis use were associated with child sleep outcomes among 11,875 children ages 9-10 controlling for covariates including prenatal substance exposure, mother's education, combined household income, parental marital status, race, child sex, and child age.

Results: Endorsement of any prenatal cannabis use was associated with symptoms of disorders of initiating and maintaining sleep, disorders of arousal, sleep wake disorders, disorders of excessive somnolence, and a summed sleep disorder score (all β > 0.

Onset of regular cannabis use and young adult insomnia: an analysis of shared genetic liability.

Study Objectives: Estimate the genetic and environmental influences on the relationship between onset of regular cannabis use and young adult insomnia.

Methods: In a population-based twin cohort of 1882 twins (56% female, mean age = 22.99, SD = 2.

Onset of regular cannabis use and adult sleep duration: Genetic variation and the implications of a predictive relationship.

Background: Limited evidence suggests that early cannabis use is associated with sleep problems. Research is needed to understand the developmental impact of early regular cannabis use on later adult sleep duration.

Methods: In a sample of 1656 adult twins (56% female, Mean age = 25.

Alcohol use, psychiatric disorders and gambling behaviors: A multi-sample study testing causal relationships via the co-twin control design.

Human laboratory studies and twin research investigating relationships between alcohol use/pathology and gambling generally have yielded contradictory results, sometimes suggesting causal relationships and common genetic risk factors. 2860 individuals (mean age: 25.60, s.