Understanding food addiction in obesity: a genetic perspective.

Background: Food addiction (FA) has gained more scientific attention but needs deeper understanding. Data indicates that the central melanocortin (MC) system through the MC4 receptor (MC4R) and its polymorphisms play a crucial role in the regulation of eating behaviour and in the motivation for the rewarding properties of food potentially leading to obesity. This may also contribute to the emergence of altered reward-related behaviors such as FA.

The place of risperidone in situ microparticles (ISM®) among long-acting injectable antipsychotics in schizophrenia treatment.

Introduction: A key challenge in managing schizophrenia is ensuring adequate adherence to antipsychotic treatment. Long-acting injectable (LAI) antipsychotics play a crucial role in improving adherence, yet certain clinical needs remain unmet, including a rapid symptom control and satisfactory efficacy/tolerability balance.

Areas Covered: Main pharmacokinetics and pharmacodynamics properties as well as the effectiveness and safety profile of risperidone in situ microparticles (ISM®) are described.

Early Maladaptive Schemas Mediate the Relationship Between Childhood Trauma and Interpersonal Problems in Eating Disorders.

Recent research highlights the role of childhood trauma in the development of eating disorders (EDs), suggesting that adverse experiences can disrupt emotional and cognitive development, leading to early maladaptive schemas (EMSs) and interpersonal problems. EMSs are psychological structures encompassing cognition, emotions, images, and bodily sensations. These EMSs are hypothesized to mediate the relationship between childhood trauma and ED pathology.

The Greater the Number of Altered Eating Behaviors in Obesity, the More Severe the Psychopathology.

: Altered eating behaviors (AEBs) are not only associated with eating disorders but also play a role in obesity. This study assessed AEBs in individuals with obesity and their association with general and eating psychopathology, using the "Eating Behaviors Assessment for Obesity" (EBA-O). The hypothesis posited that a higher frequency of pathological eating behaviors would correlate with more severe psychopathology.