Publications by authors named "Emma D Wolfe"
Financial Toxicity, Psychological Well-Being, and Quality of Life in Hematopoietic Stem Cell Transplantation.
Transplant Cell Ther
August 2025
Background: Financial toxicity is a well-documented consequence of cancer care and may disproportionately impact patients with hematologic malignancies due to the high cost and intensity of hematopoietic stem cell transplant (HSCT). This population is particularly vulnerable to the psychological consequences of financial toxicity; however, the longitudinal relationship between financial toxicity and psychological well-being-particularly positive psychological well-being-remains understudied.
Objective: To assess longitudinal associations between financial toxicity and patient-reported psychological distress (anxiety, depression, and post-traumatic stress disorder [PTSD] symptoms), positive psychological well-being (PPWB), coping, and quality of life (QOL) in patients with hematologic malignancies who received allogeneic HSCT.
: Medication adherence is essential for treatment and recovery following hematopoietic stem cell transplantation (HSCT). However, limited data exist on the most effective methods to measure adherence and the factors influencing it in HSCT patients. : A prospective longitudinal study assessed immunosuppressant medication adherence in 150 patients with hematologic malignancies undergoing allogeneic HSCT.
View Article and Find Full Text PDFA Structured Peer Support Intervention for Patients With Hematologic Malignancies Undergoing Hematopoietic Stem Cell Transplantation: Peer Support Interventionists' Perspectives.
Transplant Cell Ther
June 2025
Background: Peer support is emerging as an important component of supportive care for patients with hematologic malignancies, but it has not been robustly implemented in patients undergoing hematopoietic stem cell transplantation (HSCT).
Objectives: This qualitative study aimed to explore the experiences of peer support interventionists (participants) delivering a structured, 5-session, phone-delivered peer support intervention, the Supporting Transplant Experiences with Peer Program (STEPP) for patients undergoing HSCT.
Methods: Adult patients who underwent allogeneic or autologous HSCT for the treatment of a hematologic malignancy within the past 3 years were eligible to volunteer in this study as trained STEPP interventionists.
Background: In residency programs, the availability of faculty mentors for traditional dyadic mentorship relationships may be limited. Few frameworks exist for mentorship programs with a combined faculty and peer mentorship approach. The authors developed the Mentorship Families Program (MFP), a faculty-resident group mentorship program within a psychiatry residency program to meet the need for mentorship for a large cohort of residents.
View Article and Find Full Text PDFArticle Synopsis
- A new study is testing a five-session phone-based peer support program called STEPP, aimed at helping patients with blood cancers undergoing stem cell transplantation improve their quality of life and reduce psychological distress.
- The pilot trial will involve 90 patients, comparing those who receive the STEPP intervention to those who receive standard care, with goals for high enrollment and session completion rates.
- The study will assess how well the intervention is received and its initial impact on patient-reported outcomes like anxiety and quality of life, paving the way for a larger clinical trial in the future.
Article Synopsis
- - The study investigates how positive psychological well-being (PPWB) relates to mood and quality of life in people who have undergone hematopoietic stem cell transplantation (HSCT), using data from 158 recipients.
- - Results indicate that older age, greater social support, and certain health conditions correspond with higher PPWB levels, which are linked to improved quality of life and reduced symptoms of PTSD, anxiety, and depression.
- - The researchers suggest that future studies should explore these associations over time to better understand how PPWB affects HSCT recovery and to develop targeted interventions for improving patient outcomes.
Although peer support interventions are associated with improved patient-reported outcomes in diverse cancer populations, structured peer support programs tailored to the needs of patients undergoing hematopoietic stem cell transplantation (HSCT) are lacking. This single-arm, proof-of-concept trial aimed to refine the Supporting Transplant Experiences with Peer Program (STEPP), a structured, five-session, manualized, phone-delivered peer support intervention for patients undergoing HSCT, informed by qualitative feedback from patients. Adult patients with hematologic malignancies scheduled to undergo allogeneic or autologous HSCT were eligible to participate in the study approximately two weeks prior to their HSCT hospitalization.
View Article and Find Full Text PDFBackground: Social support is associated with improved clinical outcomes but is understudied among US immigrants. We examined two types of social support, perceived health provider support and community support, and characterized perceptions of social support among US immigrants compared with nonimmigrants.
Methods: We conducted cross-sectional data analysis on self-reported data from Health Information National Trends Survey 5, Cycle 2.
Article Synopsis
- The study focuses on the psychological challenges faced by survivors of allogeneic hematopoietic stem cell transplantation (HSCT) and tests a telephone-based positive psychology intervention called PATH to improve their well-being.
- PATH involved 9 weekly phone sessions emphasizing gratitude, personal strengths, and finding meaning in life, and aimed for high participant enrollment and session completion.
- Results showed promising improvements in gratitude, anxiety, physical function, and other psychological factors among those who participated in PATH compared to those receiving usual care.