Publications by authors named "Emily B Ambinder"

Background: The coronavirus disease of 2019 pandemic significantly disrupted health care delivery, leading to delays in diagnostic procedures.

Objective: This study aimed to examine the factors associated with delays in time from diagnostic examination to image-guided breast biopsies during the prepandemic, shutdown, and postshutdown periods.

Methods: This retrospective cohort study included 4,415 examinations with a BI-RADS 4 or 5 assessment recommending image-guided biopsy for 4,197 patients at a multisite academic institution from January 1, 2019, to December 31, 2021.

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Objective: To perform the first known investigation of differences between real-time and offline B-mode and short-lag spatial coherence (SLSC) images when evaluating fluid or solid content in 60 hypoechoic breast masses.

Methods: Real-time and retrospective (i.e.

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Introduction: Focal non-mass enhancement (NME) is a common breast MRI finding with limited data to guide management. This study aimed to assess clinical and imaging features of malignant BI-RADS 4 focal NME.

Methods: This IRB-approved, retrospective study included breast MRI exams between August 1, 2013 and September 1, 2022 yielding BI-RADS 4 focal NME lesions that underwent core biopsy or excision with available pathology result or demonstrated decrease or resolution during follow-up MRI or at least 2 years of MRI stability.

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Introduction: MRI-guided biopsy is the standard of care for breast imaging findings seen only by MRI. Although a non-zero false-negative rate of MRI-guided breast biopsy has been reported by multiple studies, there are varied practice patterns for imaging follow-up after a benign concordant MRI guided biopsy. This study assessed the outcomes of benign concordant MRI-guided biopsies at a single institution.

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Objective: To characterize the patient population using weekend and evening appointments for screening mammography versus standard appointment times across four outpatient facilities in our academic health system.

Methods: In this institutional review board-approved retrospective cohort study, there were 203,101 screening mammograms from 67,323 patients who had a screening mammogram performed at outpatient centers at a multisite academic institution from January 1, 2015, to December 31, 2022. Screening appointments were defined as "standard appointment time" (between 8 am and 5 pm on Monday through Friday) or "weekend or evening appointment time" (scheduled after 5 pm on Monday through Friday or at any time on a Saturday or Sunday).

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Objective: To assess use of mammography information systems (MISs) and explore features associated with breast imaging radiologist satisfaction.

Methods: A 22-question survey regarding MISs was distributed electronically to the Society of Breast Imaging membership between February 16, 2022 and June 28, 2022. Differences in responses between respondents satisfied and dissatisfied with their MIS were analyzed using Pearson chi-squared test, Fisher exact test, and multivariate logistic regression.

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Objective: Management of circumscribed breast masses seen on MRI is largely extrapolated from mammography and US data with limited MRI-specific data available. This study aimed to assess clinical and MRI imaging features of malignant circumscribed breast masses.

Methods: In this IRB-approved retrospective study, breast MRIs performed between April 1, 2008, and August 30, 2020, containing circumscribed masses, excluding multiple bilateral circumscribed masses, were reviewed.

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Article Synopsis
  • A study was conducted to analyze the pathology of nonmass enhancement (NME) near biopsy-confirmed malignant breast masses via preoperative MRI in newly diagnosed breast cancer patients from July 2016 to September 2019.
  • Out of 58 patients, 64% had malignant findings associated with NME, with a significant relation to a lower Ki-67 index of the primary cancer.
  • The research found that MRI measurements of suspicious enhancement often overestimated the extent of disease compared to histological analysis, suggesting that MRI may not accurately represent true tumor spread.
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Purpose To evaluate the use of ChatGPT as a tool to simplify answers to common questions about breast cancer prevention and screening. Materials and Methods In this retrospective, exploratory study, ChatGPT was requested to simplify responses to 25 questions about breast cancer to a sixth-grade reading level in March and August 2023. Simplified responses were evaluated for clinical appropriateness.

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Background: Supplemental screening with breast MRI is recommended annually for patients who have greater than 20% lifetime risk for breast cancer. While there is robust data regarding features of mammographic screen-detected breast cancers, there is limited data regarding MRI-screen-detected cancers.

Patients And Methods: Screening breast MRIs performed between August 1, 2016 and July 30, 2022 identified 50 screen-detected breast cancers in 47 patients.

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Objective: The goal of this study was to determine patient factors associated with the use of self-scheduling of screening mammograms (SMs) using an online portal.

Methods: All SMs scheduled at our multisite academic institution from January 1, 2015, to December 31, 2022, were included. The frequency of self-scheduling via an online portal was calculated per year.

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Purpose: For patients treated with neoadjuvant chemotherapy (NAC) for breast cancer, it is standard of care to perform pre- and post-NAC imaging to evaluate response to therapy prior to surgery. In this study we assess outcome metrics of magnetic resonance imaging (MRI) following NAC.

Methods: We conducted a retrospective analysis of patients with invasive breast cancer who underwent a breast MRI before and after NAC between 2016 and 2021 at a single, multisite academic institution.

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Rationale And Objective: Mammographic screening detects most breast cancers but there are still women diagnosed with breast cancer between annual mammograms. We aim to identify features that differentiate screen detected breast cancers from interval breast cancer.

Materials And Methods: All screening mammograms (n = 211,517) performed 7/1/2013-6/30/2020 at our institution were reviewed.

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This retrospective study presents 110 patients with suspected COVID-19 vaccine-related axillary adenopathy on breast MRI. Our study aimed to assess the outcomes of axillary adenopathy detected on breast MRI performed within one year after COVID-19 vaccination. The median time between the COVID-19 vaccine and breast MRI was shorter in patients with detected adenopathy compared to patients without detected adenopathy (6 weeks [2-17] versus 15 [7-24] weeks, p < 0.

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Article Synopsis
  • There is limited research on defining criteria for MRI findings with a low likelihood (≤2%) of breast cancer, making BI-RADS 3 assessments difficult and inconsistent among radiologists.
  • New data suggest that BI-RADS 3 should only apply to baseline MRIs for high-risk screenings, particularly for masses that show typical characteristic patterns of benignity.
  • The article offers an updated perspective on BI-RADS 3 assessments, focusing on current evidence and specific features that qualify for a "probably benign" classification in breast MRI.
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Purpose: This study assessed the upgrade rates of high-risk lesions (HRLs) in the breast diagnosed by MRI-guided core biopsy and evaluated imaging and clinical features associated with upgrade to malignancy.

Methods: This IRB-approved, retrospective study included MRI-guided breast biopsy exams yielding HRLs from August 1, 2011, to August 31, 2020. HRLs included atypical ductal hyperplasia (ADH), lobular carcinoma in situ (LCIS), atypical lobular hyperplasia (ALH), radial scar, and papilloma.

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Objective: To assess the relationship between sociodemographic factors and adherence rates in patients with a BI-RADS 3 assessment.

Methods: This retrospective cohort study reviewed data from all patients with a BI-RADS 3 assessment on mammography and ultrasound examinations at a single, multisite academic institution, which serves a diverse urban-suburban population, from January 1, 2015, to December 13, 2017. Appropriate follow-up was defined as returning for the first follow-up examination 3 to 9 months after the index examination.

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Rationale And Objectives: A solitary dilated duct (SDD) is a single asymmetrically dilated breast duct with diameter more than 2 mm. The Breast Imaging Reporting and Data System (BI-RADS) fifth edition recommends additional imaging and biopsy for SDDs without demonstrated benign etiology, however management of this rare entity remains controversial. This study describes practice patterns, malignancy rate, and features associated with high-risk/malignant SDDs to better stratify patients requiring biopsy versus follow-up.

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