Exposure to different PM extracts induces gliosis and changes behavior in male rats similar to autism spectrum disorders features.

Epidemiological studies have documented that exposure to fine particulate matter (PM) could affect neurodevelopment, thereby leading to autism spectrum disorders (ASD). Nevertheless, there is little laboratory data to support this epidemiological evidence. In the current study, we carried out a series of experiments to assess whether developmental exposures to different extracts of PM can result in ASD-like behavioral, biochemical, and immunohistochemical characteristics in male rat offspring.

Genomic medicine on the frontier of precision medicine.

Genomic medicine has created a great deal of hope since the completion of the Human Genome Project (HGP). Genomic medicine promises disease prevention and early diagnosis in the context of precision medicine. Precision medicine as a scientific discipline has introduced as an evolution in medicine.