Publications by authors named "Doraiswamy Jayakumar"

Article Synopsis
  • - Guided bone regeneration is a technique that uses a barrier membrane over a bone graft site to prevent soft tissue growth, allowing slow-growing bone cells to establish properly for effective bone regeneration.
  • - The combination of chitosan and gelatin creates a scaffold that enhances bone healing, with chitosan providing structure and antimicrobial benefits, and gelatin promoting cell attachment and proliferation.
  • - A systematic review of six studies found that chitosan and gelatin scaffolds significantly improved bone repair, suggesting they could be vital in treating tissue loss from conditions like periodontitis, and future research should look into other biopolymer integrations for advancement.
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Aim Guided tissue regeneration (GTR) membranes have been used to encourage the regrowth of periodontal tissues, but traditional GTR membranes may not degrade at the right rate, which can lead to complications. Multifunctional scaffolds such as chitosan and gelatin-based scaffolds are designed to have controlled biodegradation, ensuring that they remain in place long enough to support tissue regeneration. These scaffolds are included with hemostatic properties that can help control bleeding, making the procedure safer for patients.

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Herbal medicines have long been used as a traditional mode of therapy for various ailments in India. They are being used increasingly as dietary supplements to ward off common diseases. Periodontal diseases are highly prevalent and can affect up to 90% of the world population.

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Background And Aim: Autologous platelet-rich fibrin (PRF) and barrier membranes in the treatment of intrabony defects in chronic periodontitis patients have shown significant clinical benefits. This study evaluates the additive effect of autologous PRF in combination with a barrier membrane versus the use of barrier membrane alone for the treatment of intrabony defects in chronic periodontitis patients.

Methods: A randomized split-mouth design was used.

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Sulfiredoxin is a recently discovered member of the oxidoreductases family which plays a crucial role in thiol homoeostasis when under oxidative stress. A myriad of systemic disorders have oxidative stress and reactive oxygen species as the key components in their etiopathogenesis. Recent studies have evaluated the role of this enzyme in oxidative stress mediated diseases such as atherosclerosis, chronic obstructive pulmonary disease and a wide array of carcinomas.

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The aim of the present review is to systematically evaluate the additive effect of autologous platelet concentrates (APCs) in treatment of intrabony defects when used along with other regenerative procedures and when used alone in terms of clinical and radiological outcomes. A search was performed in electronic databases (i.e.

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