Factors Associated With Early Recurrence in Non-Surgically Managed Primary Spontaneous Pneumothorax.

Background: The indications for surgery in primary spontaneous pneumothorax (PSP) at first episode are clearly defined. Despite the indications, some patients avoid surgical treatment. This study examines the factors affecting early recurrence in patients who have not undergone surgical intervention.

Corona-like nanostructures: Quantum dots meet pleural fluid proteins/peptides for theranostic applications.

The incorporation of protein and peptide components into nanoparticles is a revolutionary advancement in nanotheranostics, particularly in the domain of personalised medicine. This study delves into the creation of multifunctional theranostic nanoparticles by conjugating quantum dots (QDs) with proteins and peptides sourced from the pleural fluid of lung cancer patients. Our objective is to enhance the targeting and therapeutic potential of QDs through the formation of corona-like nanostructures.

Distinct temporal profiles of AMPs and cytokines in pleural fluids from open and closed thoracic surgeries and exploration of synergy with antibiotics and wound healing effects.

Antimicrobial peptides (AMPs) play a crucial role in immune defense and wound healing. Their expression and function in pleural fluids following different thoracic surgeries remain underexplored. This study aims to compare AMP and cytokine profiles in pleural fluids from patients undergoing open and closed thoracic surgeries and assess their antimicrobial efficacy and wound healing potential.