Intravesical Pressure Monitoring: A Practical Method for Predicting Diuresis in Patients with Congestive Heart Failure.

Background: Intra-abdominal pressure (IAP) may increase in acute decompensated heart failure (ADHF) due to fluid accumulation in the splanchnic system, contributing to renal venous congestion and impaired diuresis. This study aimed to evaluate the predictive value of IAP for early diuretic response in patients with ADHF.

Methods: This prospective, single-center study included 83 patients (mean age 71.

Physiology assessment in bifurcation percutaneous coronary intervention: Insights from PROGRESS-BIFURCATION registry.

Fractional flow reserve (FFR) and non-hyperemic pressure ratios (NHPR) are established physiologic indices that can help inform the need for percutaneous coronary intervention (PCI), however, their use in patients undergoing bifurcation PCI is uncertain. The PROGRESS-BIFURCATION study is an ongoing multi-center, international registry conducted across six centers. Among 2494 bifurcation lesions treated (2271 patients), only 158 (6.

Clinical, procedural, and follow-up outcomes of percutaneous coronary intervention-related stroke: insight from the PROGRESS-COMPLICATIONS registry.

Background: Stroke is an infrequent but potentially severe complication of percutaneous coronary intervention (PCI).

Methods: The authors describe the clinical features, angiographic characteristics, and procedural and follow-up outcomes of PCI-related stroke in the PROGRESS-COMPLICATIONS registry.

Results: Of 22 503 patients who underwent PCI at 2 tertiary care centers between 2016 and 2023, 157 (0.

Multiple Versus Single Vessel CTO PCI in the Same Hospitalization: Data From the PROGRESS-CTO Registry.

Percutaneous coronary intervention (PCI) of multiple chronic total occlusions (CTOs) during a single procedure is infrequently performed and remains understudied. We compared the characteristics and outcomes of patients who underwent multiple versus single CTO PCIs during the same procedure. We analyzed data from 16,550 patients (16,876 CTO PCIs) from a large, multicenter registry.

Validation of the V-RESOLVE Score for Side Branch Occlusion in the PROGRESS-BIFURCATION Registry.

Background: We validated the Visual estimation for Risk prEdiction of Side branch OccLusion in coronary bifurcation interVEntion (V-RESOLVE) score for predicting side branch occlusion (SBO) in an independent registry.

Aims: We sought to evaluate the predictive performance of the V-RESOLVE score.

Methods: We compared the characteristics, V-RESOLVE scores, and outcomes of 791 patients (937 bifurcation PCIs) who underwent provisional bifurcation PCI performed at five centers between 2014 and 2024 from the PROGRESS-BIFURCATION registry.

Acute Kidney Injury Requiring Dialysis Following Percutaneous Coronary Intervention: Insights From the PROGRESS-COMPLICATIONS Registry.

Background: Acute kidney injury (AKI) requiring dialysis is a potentially life-threatening complication of percutaneous coronary intervention (PCI).

Aims: To assess the clinical and procedural characteristics and the outcomes of patients with AKI requiring dialysis after PCI.

Methods: We examined the clinical, procedural characteristics and outcomes of AKI requiring dialysis after PCI from a contemporary PCI complication registry (NCT05100940).

Coronary Computed Tomography Angiography for Percutaneous Coronary Intervention: Initial United States Experience With FFR Based Virtual PCI.

Background: Coronary computed tomography angiography (CCTA) and CCTA-derived fractional flow reserve (FFR) based virtual percutaneous coronary intervention (PCI) can facilitate pre-procedural planning but there are limited clinical data.

Methods: Observational cohort study of consecutive patients undergoing CCTA-guided PCI with the use of the FFR-based virtual planner, which conjointly with CCTA enables pre-procedural planning including guide catheter selection, optimal fluoroscopic angles, stent length based on predicted post-PCI FFR, as well as plaque and calcium characterization. We also assessed the correlation between FFR and invasive FFR.

The Impact of Target Vessel Diameter on the Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry.

Background: The impact of target vessel diameter on outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.

Aim: To compare the impact of target vessel diameter on CTO PCI outcomes.

Methods: We examined the association of vessel diameter with clinical, angiographic characteristics, and procedural outcomes of CTO-PCI in a large multicenter registry.

Impact of Bifurcation Angle on Side Branch Occlusion in Provisional Bifurcation Percutaneous Coronary Intervention: Analysis from the PROGRESS-BIFURCATION Registry.

Limited information exists on the impact of the bifurcation angle on side branch occlusion (SBO) in provisional percutaneous coronary intervention (PCI). We examined the procedural characteristics and outcomes of 1015 bifurcation PCIs (855 patients) that were performed using the provisional technique between 2014 and 2023 from a multicenter bifurcation PCI registry (NCT05100992). The median bifurcation angle was 60° (interquartile range [IQR] 40°-80°).

Bifurcation percutaneous coronary intervention in patients with prior coronary artery bypass graft surgery: Analysis from the PROGRESS-BIFURCATION registry.

Background: Bifurcation percutaneous coronary intervention (PCI) is understudied in patients with prior coronary artery bypass graft surgery (CABG).

Objectives: We sought to evaluate the clinical and procedural characteristics, and outcomes of bifurcation PCI in patients with versus without prior CABG.

Methods: We compared the technical, procedural characteristics and outcomes of patients with and without prior CABG among 1305 patients who underwent 1496 bifurcation PCIs at five centers between 2014 and 2024.

Impact of Isolated Side Branch Lesions on Procedural Techniques and Outcomes of Bifurcation Percutaneous Coronary Intervention.

Background: There is limited information on the impact of the isolated side branch lesions (ISBL) on the procedural techniques and outcomes of bifurcation percutaneous coronary intervention (PCI).

Aims: To examine the clinical, procedural and long-term outcomes of ISBL.

Methods: We examined the clinical, angiographic characteristics, and procedural outcomes of 1719 bifurcation PCIs in 1501 patients between 2014 and 2023 from the PROGRESS-BIFURCATION registry.

Artificial intelligence for chronic total occlusion percutaneous coronary interventions.

Artificial intelligence (AI) has become pivotal in advancing medical care, particularly in interventional cardiology. Recent AI developments have proven effective in guiding advanced procedures and complex decisions. The authors review the latest AI-based innovations in the diagnosis of chronic total occlusions (CTO) and in determining the probability of success of CTO percutaneous coronary intervention (PCI).

Dissection Techniques in Chronic Total Occlusion Percutaneous Coronary Intervention.

Background: There is limited data on dissection strategies in chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Aims: To study the differences in the baseline characteristics and procedural outcomes of antegrade CTO PCIs that used dissection strategies.

Methods: We performed a comparative analysis of antegrade dissection and re-entry CTO PCIs from the PROGRESS-CTO registry from 50 centers (2012-2024).

The Pullback Pressure Gradient: A Physiologic Index to Differentiate Focal From Diffuse Coronary Artery Disease.

Fractional flow reserve is the most widely used physiologic index to establish the functional significance of epicardial coronary artery disease (CAD). Fractional flow reserve guides clinical decisions toward or against coronary revascularization based on a single binary decision threshold indicative of myocardial ischemia. CAD pathophysiological patterns can be evaluated by assessing the distribution of pressure losses along the coronary vessel, often displayed as a "pullback curve.

Heart rate variability of interventional cardiology fellows and attendings and changes over time.

Objectives: The levels of stress experienced by interventional cardiologists (IC) while performing procedures are not well known. The study examined the IC fellow and attending stress levels using both objective (heart rate variability [HRV]) and subjective (State Trait Anxiety Inventory [STAI]) metrics across the IC fellowship.

Methods: Six ICs participated in a study conducted over 2 periods, each lasting 10 to 14 days.

Can iodixAnol ReducE the incidence of adverse renal or cardiac events in chronic total occlusion interventions (CARE-CTO): a substudy of the PROGRESS-CTO registry.

Objectives: The impact of contrast type in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) remains controversial. The authors sought to evaluate the impact of contrast medium selection on patients undergoing CTO PCI.

Methods: The authors examined the outcomes of patients who underwent CTO PCI using iso-osmolar (iodixanol) vs pooled low-osmolar contrast media (LOCM) using data from the PROGRESS-CTO registry.

Ultrasound-Assisted Catheter-Directed Thrombolytic Therapy Vs. Anticoagulation in Acute Intermediate-High Risk Pulmonary Embolism: A Quasi-Experimental Study.

Background: Given the bleeding risk associated with full-dose intravenous thrombolytic treatment and the absence of randomized clinical trial evidence, current guidelines do not recommend reperfusion treatments as first-line therapy for intermediate-high risk (IHR) pulmonary embolism (PE). The aim of this study was to evaluate the effectiveness and safety of ultrasound-assisted catheter-directed thrombolysis (USAT) compared to anticoagulation therapy alone in patients with IHR PE.

Methods: A total of 425 patients diagnosed with acute PE and determined as IHR, 203 of whom underwent USAT, and 222 patients receiving only anticoagulants as the control group, were included.

Obstructive sleep apnea syndrome in chronic total occlusion percutaneous coronary intervention; insights from the PROGRESS-CTO registry.

Objective: To examine the outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in patients with obstructive sleep apnea syndrome (OSAS).

Methods: We compared the procedural characteristics and outcomes of CTO PCIs in patients with and without OSAS in a multicenter registry.

Results: Of 7403 patients who underwent 7408 CTO PCIs between 2012 and 2024 at 47 centers, 942 (13%) had OSAS.

Outcomes of Intracoronary Brachytherapy for In-Stent Restenosis.

Because of limited alternative options, intracoronary brachytherapy (ICBT) continues to be used for treating in-stent restenosis (ISR). We examined the indications, characteristics, and outcomes of ICBT in consecutive patients who underwent ICBT for ISR between January 2014 and December 2023 at a tertiary care center. During the study period 343 patients underwent ICBT of 502 lesions.

How to Improve Radiation Protection in Interventional Cardiology Procedures.

The use of ionizing radiation during cardiac catheterization procedures poses risks to patients and medical staff, both directly and indirectly through orthopedic injuries caused by lead aprons. In this review, we summarize recent advances in radiation protection in the cardiac catheterization laboratory and discuss the effectiveness of traditional and novel radiation protection strategies and equipment.

Vascular Access-Site Complications in Chronic Total Occlusion Percutaneous Coronary Intervention.

Background: Vascular access-site complications (VASC) can occur during chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Methods: We compared the baseline and procedural characteristics, and outcomes of patients with versus without VASC in a large multicenter CTO PCI registry. VASC was defined as any of the following: small hematoma (hematoma < 5 cm), large hematoma (hematoma ≥ 5 cm), arteriovenous fistula, pseudoaneurysm and acute arterial closure.

Traditional Versus Dual Lumen Microcatheter-Assisted Parallel Wiring in Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry.

Background: The effectiveness and safety of traditional versus dual lumen microcatheter (DLMC)-assisted parallel wiring in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.

Aims: To compare traditional versus dual lumen microcatheter (DLMC)-assisted parallel wiring.

Methods: We compared the clinical and angiographic characteristics and outcomes of traditional versus DLMC-assisted parallel wiring after failed antegrade wiring (AW) in a large, multicenter CTO PCI registry.

Impact of Side Branch Predilatation on Provisional Bifurcation Percutaneous Coronary Intervention Outcomes: Insights From PROGRESS-BIFURCATION Registry.

Background: Whether side branch (SB) predilatation should be performed in patients undergoing bifurcation percutaneous coronary interventions (PCI) remains controversial.

Methods: We performed an observational cohort study across six international centers from 2013 to 2024, as part of the Prospective Global Registry of PCI in Bifurcation Lesions (PROGRESS-BIFURCATION). We analyzed procedural characteristics and in-hospital outcomes of patients undergoing provisional bifurcation PCI with and without SB lesion predilatation.