Publications by authors named "Deepika Suresh"

Eucalyptus oil is a widely available essential oil with therapeutic applications, but its toxic effects following ingestion are significant. We report a fatal case of eucalyptus oil poisoning in an adult male who mistakenly ingested 15 mL of eucalyptus oil stored in a cough syrup container. The patient developed generalized tonic-clonic seizures within minutes, followed by unresponsiveness and respiratory depression.

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Background: In patients with metabolic dysfunction-associated steatotic liver disease (MASLD), there are limited data on how changes in FIB4 and liver stiffness measurement (LSM) correlate in non-biopsy cohorts.

Aims: Our objective was to evaluate associations between changes in FIB4 and LSM in MASLD patients.

Methods: We included MASLD patients with serial VCTE from 2015-2022.

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Article Synopsis
  • Ferritin levels were examined as indicators of liver fibrosis and iron levels in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), particularly to see if high ferritin predicts disease progression.
  • A study of 7,333 MASLD patients revealed that 20% had elevated ferritin, and those with high levels showed increased mortality and liver-related events compared to those with normal levels.
  • Elevated ferritin was linked to genetic variants that promote cirrhosis but not to common gene mutations related to iron overload, suggesting different underlying mechanisms in MASLD progression.
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Background: Social determinants of health (SDOH) are becoming increasingly recognised as mediators of human health. In the setting of metabolic dysfunction-associated steatotic liver disease (MASLD), most of the literature on SDOH relates to individual-level risk factors. However, there are very limited data on neighbourhood-level SDOH in MASLD.

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Background & Aims: Non-alcoholic fatty liver disease (NAFLD) can develop in individuals who are not overweight. Whether lean persons with NAFLD have lower mortality and lower incidence of cirrhosis, cardiovascular diseases (CVD), diabetes mellitus (DM) and cancer than overweight/obese persons with NAFLD remains inconclusive. We compared mortality and incidence of cirrhosis, CVD, DM and cancer between lean versus non-lean persons with NAFLD.

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The objective was to study the effects of high glucose on the morphological changes and to observe the expression of apoptosis regulatory proteins in the developing retina in vivo using zebrafish embryos. Wild-type male and female zebrafish were allowed for normal mating and the fertilized eggs were collected and exposed to hyperglycemic conditions (25 mM D-glucose) for 96 h. The embryos were subjected to various morphological and histological analyses in a time-dependent manner.

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Patient and family communication is a well-known factor associated with improved patient outcomes. During the COVID-19 pandemic, visitation restrictions meant communication with patients and their families became a challenge, particularly with intubated patients in the intensive care unit. As the hospital filled with COVID-19 patients, medical students and physicians at Albany Medical Center identified the urgent need for a better communication method with families.

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Three induced pluripotent stem cells (iPSC) clones NCCSi007-A, NCCSi007-B and NCCSi007-C were generated from CD4T cells of a 38 years old male patient suffering from liver cirrhosis- alcoholic and minimal hepatic encephalopathy of Indian origin. The CD4T cells of the patient were reprogrammed using integration free, Sendai viral vector system. Each of the three iPSC clones showed high alkaline phosphatase (ALP) activity, expressed pluripotency markers OCT4, SOX2, NANOG, KLF4, SSEA-4, TRA-1-60, showed normal male karyotype (46, XY) and exhibited multi-lineage differentiation.

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In the United States, there are more than 400,000 girls and young women of reproductive-age with a history of cancer. Cancer treatments including surgery, chemotherapy, targeted therapy, and radiation can adversely impact their reproductive health. This review discusses infertility, contraception, and adverse pregnancy and child health outcomes in reproductive-aged cancer survivors, in order to increase awareness of these health risks for survivors and their healthcare providers.

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