Association of patient and physician characteristics with androgen-deprivation-therapy intensification in patients with de novo hormone-sensitive metastatic prostate cancer: A population-based study.

Introduction: Treatment intensification with androgen receptor signaling inhibitors and/or chemotherapy is guideline recommended for patients with de novo metastatic hormone-sensitive prostate cancer (mHSPC). However, most patients only receive androgen deprivation therapy monotherapy. The aim was to identify physician-, patient-, and tumor-related factors associated with the receipt of treatment intensification.

Single-center Experience With Surgical Management of Tumor Thrombus Intravascular Extension in Pediatric Renal Neoplasms: Case Series.

Objective: To evaluate surgical strategies and outcomes for children with intravascular extension of pediatric renal tumors by reviewing intraoperative observations and individual surgical challenges.

Methods: A retrospective chart review was undertaken on patients undergoing radical nephrectomy at our institution between 2005 and 2023. Patients identified with intravascular (vena cava) extension were included.

Prostatic Stents for the Management of Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction.

Prostatic stents offer a minimally invasive alternative for the management of benign prostatic obstruction. Efficacy has been demonstrated for stents that have already been approved, and investigational stents show promise. Long-term safety, durability, and patient selection are key factors for widespread adoption.

Identifying predictors of in-hospital mortality in patients with emphysematous pyelonephritis: insights from a large retrospective cohort.

Objectives: The purpose of this study was to investigate the predictors of in-hospital mortality of patients with emphysematous pyelonephritis (EP) by type of management.

Methods: Retrospective data were collected on 176 patients with EP who had undergone treatment at our hospital between 2011 and 2019. Data collected included demographic characteristics, clinical presentations, management strategies, and survival rates.

Does marginalization status and distance from the hospital impact the timing of pediatric pyeloplasty in a universal access-to-care system?

Introduction: Prior research in the U.S. suggests that marginalized populations tend to undergo pyeloplasty earlier, likely reflecting concerns about the challenges of reliable followup care in this population.

Secondary malignancies after treatment of testicular germ cell tumors: a systematic review & meta-analysis.

Background: Testicular germ cell tumours (TGCTs) are the most common malignancy in men 15-35 years of age. Management options for men with TGCTs include surgery, radiation and/or chemotherapy. Given TGCTs' excellent survival, most patients live long enough to experience delayed treatment toxicities, warranting careful consideration of therapeutic decisions.

Assessing Canadian medical students' confidence in undergraduate urologic training and preferences for teaching methods.

Introduction: Given the aging population, urologic conditions are increasingly prevalent in primary care, necessitating well-prepared medical graduates to recognize and manage essential complaints. This study assessed medical students' confidence in managing common urologic conditions, identified preferred teaching methods, and examined the role of the Canadian Undergraduate Urological Curriculum (CanUUC) in their education.

Methods: A survey was distributed to third- and fourth-year Canadian medical students, assessing their self-confidence in history taking, diagnosis, management planning, and physical examination for 12 urologic conditions.

Payments by Drug and Medical Device Manufacturers to Society of Urologic Oncology Fellowship Program Directors.

Introduction: This study aims to characterize payments by drug and medical device manufacturers to current program directors (PDs) of the Society of Urologic Oncology (SUO)-accredited fellowship programs in the United States.

Methods: PDs were identified from SUO fellowship websites as of February 2024. Demographic data, educational background, and scholarly metrics were collected through an online search.

A living scoping review and online repository of artificial intelligence models in pediatric urology: Results from the AI-PEDURO collaborative.

Introduction: Artificial intelligence (AI) is increasingly being applied across pediatric urology. We provide a living scoping review and online repository developed by the AI in PEDiatric UROlogy (AI-PEDURO) collaborative that summarizes the current and emerging evidence on the AI models developed in pediatric urology.

Material And Methods: The protocol was published a priori, and Preferred Reporting Items for Systematic Review and Meta-analysis Scoping Review (PRISMA-ScR) guidelines were followed.

Decision aid for surgical management of benign prostatic hyperplasia - Assessing acceptability of the French version.

Introduction: Exploring all surgical interventions for benign prostatic hyperplasia (BPH) can be time-consuming. We developed the first online CUA-endorsed BPH surgical Patient Decision Aid (PtDA), including all guideline-approved surgical modalities. Our study assesses the acceptability of the tool's French version (FRv) among patients and urologists.

Disproportionality Analysis of Hypotension-Related Adverse Drug Reactions Associated With Type 1a Selective Alpha-Blockers in VigiBase.

Introduction: Some evidence suggests no association between type 1a (T1a) selective alpha-blockers and hypotension-related adverse drug reactions (HR-ADRs), although safety concerns still exist. We sought to investigate the association of HR-ADRs with selective T1a blockers and identify at-risk groups.

Methods: We used disproportionality analysis to detect signals of HR-ADRs (dizziness, fainting, falls, and fractures) reported with selective T1a blocker use (tamsulosin and silodosin) in VigiBase, a global database of individual case safety reports.

Five years of competency-based medical education in Canadian urology A national survey of senior resident and faculty satisfaction and perspectives.

Introduction: In 2018, competency-based medical education (CBME) was introduced to Canadian urology residency training. We examined learner and faculty experiences with CBME five years post-implementation.

Methods: Two online surveys were developed from a scoping review of CBME literature and expert consultation.

Can the free/total psa ratio predict undetected intraductal carcinoma and cribriform pattern at biopsy?

Background: Intraductal carcinoma (IDC) and cribriform pattern (Crib) of prostate cancer are recognised as independent prognosticators of poor outcome, both in prostate biopsies and radical prostatectomy (RP) specimens.

Objective: This study aimed to determine the predictive value of Free-to-total PSA ratio (FPSAR) in identifying missed IDC/Crib at the time of biopsy as compared to the final surgical specimen.

Materials And Methods: Patients who underwent RP between January 2015 and December 2022 were included in the study.

Proportion of Gleason Score ≥8 Prostate Cancer on Biopsy and Tumor Aggressiveness in Matched Cohorts of East Asian and Non-East Asian Men.

Background: Historically, Asia had a lower prostate cancer (PCa) incidence and mortality compared with Western countries, but the gap is narrowing. Paradoxically, Asians have been reported to present with more advanced disease though more favorable outcomes. Despite PCa becoming an emerging health priority in East Asia, our knowledge remains limited.

WATER versus WATER II 5-year update: Comparing Aquablation therapy for benign prostatic hyperplasia in 30-80-cm and 80-150-cm prostates.

Objective: This study aims to compare the long-term outcomes of Aquablation for small-to-moderate (30-80 cm) prostates with the outcomes for large (80-150 cm) prostates at 5-year follow up.

Methods: The Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue (WATER; NCT02505919) is a prospective, double-blind, international clinical trial encompassing 116 patients, examining Aquablation versus transurethral resection of the prostate (TURP) for LUTS/BPH in prostates sized between 30 and 80 cm. In parallel, WATER II (W-II; NCT03123250), a prospective, multicentre, single-arm international clinical trial, explores Aquablation outcomes in prostates ranging from 80 to 150 cm.

Industry-Sponsored Research Funding to Urologists in the United States Between 2014 and 2022.

Introduction: Urologists face challenges in obtaining public research funding, leading to increasing reliance on the industry for research support. This study aimed to examine the extent and trends in industry-sponsored research payments to urologists from 2014 to 2022 in the United States.

Methods: We identified all US urologists using the Centers for Medicare and Medicaid Services National Plan and Provider Enumeration System database and extracted their industry-sponsored research payments data from the Centers for Medicare and Medicaid Services Open Payments Database.