Electronic cigarette use in Saudi Arabia: a cross-sectional study on emerging trends and public health concerns.

Background: Electronic cigarette (e-cigarette) use has become increasingly popular worldwide, including in Saudi Arabia, especially among younger individuals. This study investigates the patterns, motivations, and perceptions of e-cigarette use to inform public health interventions and policy.

Methods: This descriptive cross-sectional study surveyed traditional cigarette smokers and ex-smokers above 18 in Saudi Arabia using an online questionnaire distributed via social media with convenience and snowball sampling.

"Know your medicines, know your health"-public perspectives on medicines and health awareness campaigns.

Background: Irrational medication use is likely to result in therapeutic failure and disease progression. One way to increase public awareness about appropriate medication use is to design and deliver a public health medicine awareness campaign. This study aims to assess the public's attitudes and experiences related to medication use and health awareness campaigns in Saudi Arabia.

Risk of osteoporotic fractures in menopausal women with common mental health diagnoses prescribed SSRIs/SNRIs: cohort and self-controlled case series analyses.

Unlabelled: In a population-based cohort study of menopausal women with common mental health diagnoses, SSRIs/SNRIs were associated with a 32% increased risk of osteoporotic fractures. The risk of osteoporotic fractures was particularly increased for longer periods of treatment with SSRIs/SNRIs (> 5 years) and in younger menopausal women (< 50 years old).

Purpose: To investigate the association between selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) and the risk of osteoporotic fractures (OF) in menopausal women with common mental health diagnoses (CMHD).

Antidepressant medications in women aged 40 and older and the risk of fragility fractures: a systematic literature review and meta-analysis.

Introduction: Antidepressants and menopause are risk factors which are independently associated with an increased risk of fractures. This review aims to investigate the risk of fragility fractures in women aged 40 and older and prescribed antidepressants.

Methods: A literature search was conducted using PubMed, Ovid Embase, Ovid PsychINFO, Web of Science, and Scopus from inception to 1 June 2024.

Phosphodiesterase Type 5 Inhibitors in Men With Erectile Dysfunction and the Risk of Alzheimer Disease: A Cohort Study.

Background And Objectives: Repurposing phosphodiesterase type 5 inhibitors (PDE5Is) as drugs for Alzheimer disease (AD) risk reduction has shown promise based on animal studies. However, evidence in humans remains inconclusive. Therefore, we conducted a cohort study to evaluate the association between PDE5I initiation compared with nonuse and the risk of developing AD in men with erectile dysfunction (ED).

Trends in the incidence of dementia in people with hypertension in the UK 2000 to 2021.

Introduction: We investigated trends in the incidence of dementia in UK adults with hypertension.

Methods: Primary care electronic health records from IQVIA Medical Research Data UK, previously known as THIN, were used to identify 2,133,118 adults aged ≥40 years with hypertension over 2000 to 2021. The annual incidence rate and average annual percentage change in recorded dementia diagnoses were estimated and stratified by sex, 10-year age bands, Townsend deprivation quintiles and dementia subtype.

Hormone replacement therapy prescribing in menopausal women in the UK: a descriptive study.

Background: Recent studies on the prescribing of hormone replacement therapy (HRT) medicines to treat symptoms of menopause are lacking.

Aim: To describe the prescribing of HRT in a cohort of UK menopausal women.

Design & Setting: Population-based drug utilisation study using IQVIA Medical Research Database (IMRD-UK).