Research progress on the food preservation effects exploiting the antifungal properties of thymol.

Thymol is a major monoterpene compound from plants. Thymol exhibits antifungal, antioxidant, and anti-inflammatory properties. Over the past few years, extensive research has underscored the pivotal role of thymol in delaying postharvest senescence in fruits and vegetables, suppressing fungal growth in meat products, and enhancing the shelf life of meat and processed foods.

Clinical Utility of Transcatheter PFO Exploration in Cryptogenic Stroke Patients With Negative TEE but High Suspicion of PFO-Related Etiology.

Background: Patent foramen ovale (PFO) has been identified as a potential risk factor for cryptogenic stroke (CS). Although transesophageal echocardiography (TEE) is considered the gold standard for PFO detection, false-negative results remain a clinical concern, particularly in CS patients with high suspicion of PFO-related etiology.

Aims: To evaluate the clinical utility of transcatheter PFO exploration (TPFOE) in CS patients with negative TEE findings but high suspicion of PFO-related etiology.

How does the degree of phosphorylation substitution affect the protective effect of long-chain inulin on the quality deterioration of frozen dough?

This study compared the effects of phosphorylated modified long-chain inulin (PF) with low (PF1), medium (PF3), and high (PF6) degrees of substitution on the rheological, thermal, gluten network depolymerization characteristics, and microstructure of unfrozen and frozen dough. The results showed that PF increased G', G", Tp, and ΔH of unfrozen and frozen dough. Gluten protein analysis revealed that PF significantly increased the SS and α-helix content in gluten, with 3 %FPF3 showing an 11.

Blockade of metastasis by targeting circulating tumor cells with platelet encapsuled oncolytic adenovirus.

Host immune elimination largely limits the application of oncolytic viruses in clinics. Here, we rationally design a bioactive platelet-based oncolytic adenovirus delivery system. Upon loading adenoviruses, platelets are transformed to a pro-endocytosis status, which facilitates their internalization by circulating tumor cells (CTCs).

Branched DNA for disease diagnosis and therapy.

DNA exhibits remarkable versatility, which is attributed to its inherent molecular recognition capabilities, programmable sequences, and excellent biocompatibility. Among its various topological forms, branched DNA (bDNA), including Y-shaped DNA (Y-DNA), X-shaped DNA (X-DNA), etc., stands out as a fundamental building block for fabricating functional DNA-based materials and has demonstrated great promise across diverse applications in recent years.