Documentation of social determinants of health for patients with type 2 diabetes in Epic Cosmos.

Objectives: Type 2 diabetes (T2D) is a growing public health burden with persistent racial and ethnic disparities. . This study assessed the completeness of social determinants of health (SdoH) data for patients with T2D in Epic Cosmos, a nationwide, cross-institutional electronic health recors (EHR) database.

Bidirectional Relationship between the BDNF Gene and miRNA: Implications for PD Pathogenesis.

Parkinson's disease (PD) is a neurological degenerative condition that primarily affects older people. Although reduced motor skills, stiffness, dyslexia, and other motor symptoms predominate in PD, the nonmotor symptoms, such as cognitive impairment, also play an important part in the PD-affected brain. Studies have reported that the brain-derived neurotrophic factor () has a pivotal role in monitoring the nonmotor symptoms of PD.

Improving outcomes in paediatric high-grade osteosarcoma: Insights from a retrospective survival study.

Background: High-grade osteosarcoma is the most prevalent primary malignant bone tumor in children and adolescents. Despite advancements in chemotherapy and surgical techniques, survival rates have stagnated, particularly in patients presenting with metastases or poor chemotherapeutic response. This study aims to evaluate survival outcomes and identify prognostic factors influencing overall survival in pediatric osteosarcoma patients treated at a tertiary care center.

Enhancement of genetic gain for early seedling vigor traits through marker-assisted pedigree selection in rice ( L.).

Unlabelled: Early Seedling Vigor (ESV) is a critical trait for direct-seeded rice (DSR), as it promotes rapid seedling establishment and effective weed suppression. Enhancing ESV is therefore essential for developing varieties adapted to DSR conditions. This study aimed to accelerate genetic gain for ESV traits through Marker-Assisted Pedigree Selection (MAPS) by leveraging reported quantitative trait loci (QTLs).