Histone acetylation by SAGA Complex but not by NuA4 Complex is Required for filamentation programme in Candida albicans.

Candida albicans, a major human fungal pathogen undergoes filamentation from yeast to hyphal state under filamentation-inducing conditions. Gcn5 and Esa1 are key histone H3 and H4 acetyltransferases, respectively, encoded by the budding yeast and other eukaryotes. While Gcn5, a subunit of the SAGA complex, and Esa1, a subunit of the NuA4 complex are critical for C.

Bowel Health, Laxative Use, and Cognitive Function in Older Puerto Rican Adults.

Bowel dysfunction and habitual laxative use are indicators of poor gastrointestinal (GI) health and are inversely associated with cognitive function. These associations are understudied in Latino and Hispanic populations. Therefore, we examined the associations between bowel frequency, stool type, laxative use, and cognitive function in the Boston Puerto Rican Health Study (BPRHS).

Nature-based solutions for enhancing CO sequestration and rehabilitating degraded lands through silvo-aromatic system and soil moisture conservation techniques.

Ravine land is one of the most degraded lands which results from extreme soil erosion. The soil fertility in these lands is low which affects plant survival, making the cultivation of arable crops impractical. However, with the use of soil moisture conservation (SMC) techniques, the productivity of these areas can be significantly enhanced.

Efficacy and safety of ayurvedic intervention (Sarpgandha Mishran) vs amlodipine for Stage-I primary hypertension- study protocol for a prospective Double-Dummy, Double-Blind, placebo-controlled Randomized Clinical Trial.

Background: Hypertension presents as a modifiable risk factor for cardiovascular diseases, with approximately two-thirds of the global hypertensive population concentrated in low- and middle-income nations. Sarpagandha Mishran is an Ayurveda intervention utilized for the management of hypertension. The objective of the study is to assess the clinical efficacy and safety of Sarpgandha Mishran in the Management of Stage-I Hypertension.