Lowering the osteotomized level of fibular osteotomy reduces neuromuscular complications while maintaining clinical efficacy in treating medial compartment knee osteoarthritis: a retrospective comparative cohort study.

Background: Partial fibular osteotomy (PFO) offers a minimally invasive strategy for treating medial compartment knee osteoarthritis (MKOA), yet its proximity to the peroneal nerve raises concern for postoperative neuropathy. This study investigated whether lowering the osteotomy site from the upper third to the mid-third of the fibula reduces nerve complications without compromising clinical efficacy.

Methods: We retrospectively reviewed 77 consecutive patients who underwent unilateral PFO from March to December 2018.

Utilizing Evolved Extramedullary Techniques for Conventional Knee Arthroplasty in Post-traumatic Knee Arthritis With Retained Hardware: A Retrospective Analysis.

Introduction For post-traumatic knee arthritis with retained implants, performing conventional primary total knee arthroplasty (TKA) can be challenging due to altered bony structures or mechanical obstructions. Without current computer-aided navigation, we can still perform conventional TKA by extramedullary means according to the parallelism and the reference to inherent anatomical landmarks. In this study, we aim to present a novel extramedullary method applied during conventional total knee arthroplasty (TKA) and the clinical outcomes observed in our series.

Anterior tibial artery pseudoaneurysm as a rare technical complication after corrective fibular osteotomy: a case report.

Introduction: Partial fibular osteotomy has been recognized as a surgical alternative to treat medial compartment osteoarthritis of the knee. Related peroneal neuropathies are of concern among the relatively few complications after this procedure. In our clinical practice, the osteotomy level has therefore been modified to avoid the above defects.

Proximal fibular osteotomy relieves pain in spontaneous osteonecrosis of the knee: A retrospective study.

Spontaneous osteonecrosis of the knee (SONK) causes knee pain and joint motion limitation. Ischemia or insufficiency fracture may be the cause, but no consensus has been developed. Proximal fibular osteotomy (PFO) has been reported to relieve pain from osteoarthritis through medial compartment decompression.

Surface Modification of Direct-Current and Radio-Frequency Oxygen Plasma Treatments Enhance Cell Biocompatibility.

The sand-blasting and acid etching (SLA) method can fabricate a rough topography for mechanical fixation and long-term stability of titanium implant, but can not achieve early bone healing. This study used two kinds of plasma treatments (Direct-Current and Radio-Frequency plasma) to modify the SLA-treated surface. The modification of plasma treatments creates respective power range and different content functional OH groups.

Factors affecting the outcomes of modified tension band wiring techniques in transverse patellar fractures.

Introduction: Modified tension band wiring has been widely used to treat transverse patellar fractures. However, few studies have evaluated the clinical outcomes using different methods of Kirschner wire bending, location of the tension band, and depths of Kirschner wires. Thus, we tried to clarify these factors according to our clinical outcomes.

Frequent Dental Scaling Is Associated with a Reduced Risk of Periprosthetic Infection following Total Knee Arthroplasty: A Nationwide Population-Based Nested Case-Control Study.

Oral bacteremia has been presumed to be an important risk factor for total knee arthroplasty (TKA) infection. We aimed to investigate whether dental scaling could reduce the risk of TKA infection. A nested case-control study was conducted to compare 1,291 TKA patients who underwent resection arthroplasty for infected TKA and 5,004 matched controls without infection in the TKA cohort of Taiwan's National Health Insurance Research Database (NHIRD).

Fabrication of gelatin-strontium substituted calcium phosphate scaffolds with unidirectional pores for bone tissue engineering.

This study fabricated homogeneous gelatin-strontium substituted calcium phosphate composites via coprecipitation in a gelatin solution. Unidirectional porous scaffolds with an oriented microtubular structure were then manufactured using freeze-drying technology. The resulting structure and pore alignment were determined using scanning electron microscopy.

Engineering three-dimensional structures using bio-inspired dopamine and strontium on titanium for biomedical application.

The excellent mechanical properties and chemical stability of titanium and its alloys have led to their wide use as a material for dental and orthopaedic implants. However, the bio-inert nature of these materials must be overcome to enhance cell affinity and cell function following implantation. Effective implants require strong interfacial bonding, mechanical stability, osteoblast attachment, enhanced spreading and growth during early stages, and induced differentiation and mineralization in later stages.

Incidence and risk of venous thromboembolism among Taiwan osteoporotic fracture population under osteoporosis pharmacological treatments.

Context: There was no clear evidence for the association between oral bisphosphonates or raloxifene and venous thromboembolism (VTE). There might also be ethnic differences in VTE risk.

Objective: The purpose of this study was to compare the incidence and risk of VTEs for different classes of osteoporosis drugs in the Taiwanese osteoporotic fracture population.

The severity of the long head biceps tendinopathy in patients with chronic rotator cuff tears: macroscopic versus microscopic results.

Background: This study investigated the histopathology of the long head of biceps (LHB) tendon and correlated the findings with the macroscopic appearances of the LHB and the size of rotator cuff tears (RCTs) in patients with chronic RCTs.

Methods: We compared biopsy specimens from LHBs in 34 patients with chronic RCTs and grossly normal LHBs in 8 patients undergoing shoulder hemiarthroplasty (controls). Duration of preoperative symptoms, the severity of RCTs, and macroscopic appearance of LHBs were recorded, classified, and compared with the histologic grading and apoptosis index of terminal deoxynucleotide transferase-mediated biotin-deoxy uridine triphosphate nick-end labeling (TUNEL) assays of LHBs.

Comparative effectiveness of osteoporosis drugs in preventing secondary nonvertebral fractures in Taiwanese women.

Context: The evidence for relative effectiveness of osteoporosis drugs in secondary prevention of nonvertebral fractures was unclear and could not be extrapolated to the Asian population.

Objective: The objective of the study was to compare the relative effectiveness of different classes of osteoporosis drugs in secondary prevention of nonvertebral fractures in Taiwanese women.

Design: This was a retrospective cohort study from 2003 to 2007, with up to 6 years of follow-up.

Effects of tourniquet use on blood loss and soft-tissue damage in total knee arthroplasty: a randomized controlled trial.

Background: Although tourniquets are widely used in total knee arthroplasty, their effectiveness in reducing blood loss and their influence on the postoperative course remain unclear. Tourniquet-related soft-tissue damage is a related concern. We performed a prospective, randomized, controlled trial to clarify the effect of tourniquets in total knee arthroplasty.

Kinematic analysis of leg alignment during conventional versus navigated total knee arthroplasty: initial results of a prospective study.

Current kinematic navigation systems provide real-time spatial analyses of leg alignments during total knee arthroplasty (TKA) instead of delayed radiographic verification after surgery. A prospective study was conducted to investigate leg alignments of TKAs that underwent different surgical guidance [intramedullary (IM) jig-based vs. navigation-assisted] using a kinematic navigation system.

[Reducing blood preparation for total knee arthroplasty: a practical approach].

Background & Problems: The rate of allogenic blood preparation for an elective total knee arthroplasty (TKA) has been as high as 100% at our institute. However, most (76.2%) of these preparations were wasted.

An effective method to reduce ischemia time during total knee arthroplasty.

Background/purpose: Because of controversy regarding timing of tourniquet release during total knee arthroplasty (TKA), a closed arthrotomy as a tamponade for effective hemostasis was used to save ischemia time. The study was to verify the safety and efficacy on clinical issues.

Methods: A prospective cohort study was conducted on 72 consecutive unilateral primary TKAs.

Delayed superficial femoral artery pseudoaneurysm following distal femoral shaft fracture: a case report.

A 69-year-old man presented with an expanding tissue mass over the medial aspect of his left thigh 6 weeks after a fracture of the distal femur shaft. Imaging studies confirmed a rare traumatic pseudoaneurysm of the superficial femoral artery. For the massive hematoma and persistent exsanguinating hemorrhage, staged interventions were taken.

Tourniquet use in total knee arthroplasty: a meta-analysis.

Purpose: The use of an intraoperative tourniquet for total knee arthroplasty (TKA) is a common practice. However, the effectiveness and safety are still questionable. A systematic review was conducted to examine that whether using a tourniquet in TKA was effective without increasing the risk of complications.

Blood loss after minimally invasive total knee arthroplasty: effects of imageless navigation.

A prospective cohort study of 100 patients undergoing primary minimally invasive total knee arthroplasty was carried out to determine blood loss after this procedure and to examine the efficacy of navigation on blood saving. The patients were divided into two groups according to the surgical technique, and underwent either computer-assisted navigation or manual procedures. All operations were performed by a single surgeon using an identical approach.

Non-drainage is better than 4-hour clamping drainage in total knee arthroplasty.

The role of wound drainage in total knee arthroplasty (TKA) is controversial. The use of drainage was believed to be effective in decreasing hematoma formation, but it inevitably increases bleeding because the tamponade effect of a closed and undrained wound is eliminated. Clamping the drain tube in the first 4 hours after TKA can temporarily recreate a tamponade effect for bleeding control.

Argon-plasma-treated chitosan: surface characterization and initial attachment of osteoblasts.

Chitosan is a biocompatible, biodegradable and non-toxic material. It is also an advanced material used for wound dressings, drug and gene delivery, and tissue engineering. In this study, we treated chitosan film with argon plasma and characterized both its physical and chemical properties.

Elevated temperature trends after total knee arthroplasty.

Fever after total knee arthroplasty (TKA) is a common phenomenon. However, the pattern of temperature change and its correlation with perioperative factors remain unclear. The purpose of this study was to define the trend of postoperative body temperature in patients undergoing TKA.

Temporary drainage clamping after total knee arthroplasty: a meta-analysis of randomized controlled trials.

Drainage-clamping methods are thought to be effective in reducing blood loss after total knee arthroplasty (TKA). We conducted a systematic review to examine if these methods were effective without increasing the risk of complications. After a comprehensive search, 6 randomized controlled trials involving 603 knees and comparing clamping drainage and the immediate release of the drain after elective TKA were included in this analysis.

A comparative study of the physical and mechanical properties of three natural corals based on the criteria for bone-tissue engineering scaffolds.

Coral has been used for bone grafts since 1970. Because coral has the advantages of good osteoconduction, biocompatibility, and biodegradation, it is also suitable for scaffolds used in bone-tissue engineering. However, the skeletons of different species of corals often vary significantly, and very few studies focus on the assessment of the permeability and mechanical properties of coral structure.

Amelioration of collagen-induced arthritis in rats by adenovirus-mediated PTEN gene transfer.

Objective: The phosphatidylinositol 3-kinase (PI 3-kinase)/Akt pathway is known to be activated in rheumatoid arthritis (RA) synovial tissue, which impacts cell growth, proliferation, survival, and migration. Phosphatase and tensin homolog deleted from chromosome 10 (PTEN) functions as a negative regulator of PI 3-kinase signaling, thus blocking Akt activation. The aim of this study was to examine the effect of PTEN gene transfer in rats with collagen-induced arthritis (CIA).