Objectives: To explore the relationship between brain structural connectivity and polycystic ovary syndrome (PCOS).
Design: Two-sample Mendelian randomization (2SMR) was conducted by querying a relevant European population genome-wide association studies (GWAS) database about the anatomical connections of the brain and polycystic ovarian syndrome from the Ieu Open GWAS Project database. Two hundred six brain structural connectivity-related single-nucleotide polymorphisms (SNPs) were evaluated as instrumental variables (IVs).
Immun Inflamm Dis
October 2024