Publications by authors named "Chun-lin Xiong"
Association of procalcitonin with voriconazole concentrations: a retrospective cohort study.
BMC Infect Dis
September 2024
Article Synopsis
- Inflammation may pose a risk for voriconazole (VCZ) overdose, while procalcitonin (PCT) is a marker for bacterial infections; the link between PCT and VCZ serum levels is under investigation.
- A study involving 147 patients treated with VCZ from August 2017 to August 2021 found a significant association between PCT levels and VCZ trough concentrations (VCZ-C), indicating higher PCT correlates with increased VCZ-C.
- Results showed that for each fold increase in PCT, VCZ-C increased by 0.32 µg/mL in unadjusted analyses and slightly less in adjusted models, suggesting that PCT could be a useful biomarker for monitoring
[Investigation into the serum uric acid level of the residents in Henglan town of Zhongshan city].
Nan Fang Yi Ke Da Xue Xue Bao
April 2009
Article Synopsis
- The study aims to explore how serum uric acid (SUA) levels relate to cardiac cerebrovascular disease among coastal residents, offering a potential basis for prevention.
- It involved 3,111 participants from an annual physical exam, dividing them into hyperuricemia and control groups based on SUA levels.
- Findings indicate a higher incidence of hyperuricemia in males (21.8%) than females (17.6%), along with a positive correlation between SUA levels and factors like cholesterol and body weight, suggesting SUA may be a significant risk factor for heart disease.
[Emergence of 16S rRNA methylase gene rmtB in Klebsiella pneumoniae isolates from the inpatients in Zhejiang Province, China].
Zhonghua Liu Xing Bing Xue Za Zhi
September 2008
Objective: To investigate the presence and genetic background of 16S rRNA methylase gene and Aminoglycoside modifying enzymes (AMEs) genes in Klebsiella pneumoniae isolated from the People's Liberation Army 98th Hospital, Huzhou district, Zhejiang province, China.
Methods: 25 strains of Klebsiella pneumoniae were isolated from the inpatients between September, 2005 and April, 2006. 6 kinds of 16S rRNA methylase gene (including armA, rmtA, rmtB, rmtC, rmtD and npmA), 6 kinds of AMEs genes [including aac (3)-I, aac (3)-II, aac (6')-I, aac (6')-II, ant (3")-I and ant (2")-I], intI1, intI2, intI3, mercuric reductase gene merA (merA gene were the collective genetic markers of transposons of Tn21 and Tn501) and tnpA (tnpA gene were the collective genetic markers of transposons of Tn1, Tn2,Tn3 and Tn1000) were analyzed by PCR and verificated by DNA sequencing.