Predictors for change in cough-related quality of life and symptom severity in acute cough: results of an observational pharmacy-based study.

Background: Acute cough is a common symptom, frequently linked to respiratory tract infections. Although self-limiting, acute cough can significantly affect patients' quality of life (QoL), causing discomfort, disrupting sleep, and hindering daily activities. Identifying factors contributing to changes in cough-related QoL (crQoL) and severity of symptoms (SoS) is essential for developing personalised treatment approaches and enhancing patient care.

Quality of patient-reported outcome measures for acute bronchitis: a systematic review of instruments and measurement properties.

Background: Patient-reported outcome measures (PROMs) are standardized questionnaires for the assessment of health outcomes directly from the patient. A systematic evaluation of the quality of PROMs for acute bronchitis (AB) and acute cough due to (lower) respiratory tract infection or common cold has not yet been performed. The present study aimed to systematically review the quality of available PROMs for AB and acute cough due to (lower) respiratory tract infection or common cold for use in adults and children.

A multidisciplinary Delphi consensus on the modern definition of pruritus: Sensation and disease.

Background: The definition of pruritus (synonym: itch) dates back to the 17th century and does not address the complexity of the sensation or the nature of pruritus as a disease.

Objective: Elaborate a new definition of pruritus comprising emotional aspects, stages and causal attributes.

Methods: In a pre-Delphi phase, stakeholders from pruritus-relevant global societies and patients elaborated itch definition proposals.

Social support and recovery in acute respiratory distress syndrome survivors: a prospective cohort study.

Background: Social support (SS) may contribute to the long-term recovery of critical illness survivors. This study focuses on survivors of acute respiratory distress syndrome (ARDS) to investigate the causal relationship between SS and health-related quality of life (HRQoL) and healthcare utilisation in critically ill patients.

Methods: A cohort study with 877 ARDS survivors in 61 intensive care units (ICUs) was conducted in Germany between 2014 and 2019.

Content validation of the German version of the PROMIS 29+2 v2.1 in patients with post COVID-19 condition. Short report.

Background: Post-COVID-19 disease (PCC) impairs health-related quality of life (HRQoL), making its assessment crucial. Patient-reported outcome measures (PROMs) capture patients' perspectives on individual outcomes, such as HRQoL. The PROMIS 29+2 v2.

Depression does not moderate the association between beliefs about medicines and medication adherence in patients with rheumatoid arthritis: A longitudinal study.

Non-adherence is common in people with rheumatoid arthritis (RA). According to the 'necessity-concerns framework', beliefs about the necessity and concerns about prescribed medications influence adherence. The present study's objective was to investigate whether depression moderates associations between beliefs about medicines and adherence among people with physician-diagnosed RA in a longitudinal study ( = 361; 31% male, mean age [SD] 60.

Integrated Psychosocial Care in Intensive Care (IPS-Pilot): Protocol for the Systematic, Multimethod Development of a Complex Intervention (Phase A).

Background: There is a high, co-dependent strain on health care professionals (HCPs), patients, and their relatives in intensive care units (ICUs), leading to long-term mental, physical, and occupational consequences. To date, there is no systematic intervention to address this growing problem.

Objective: The aim of the IPS-Pilot (German: Integrierte Psychosoziale Versorgung; English: "Integrated Psychosocial Care") project is the development (phase A) and pilot testing (phase B) of an integrated and complex psychosocial care intervention for HCPs, patients, and their relatives in ICUs.

The Holm and Cordoba Urinary Tract Infection Score: Translation, Linguistic and Content Validation of the German Version of a Patient-Reported Outcome Measure to Assess Symptoms, Bothersomeness and Impact of Uncomplicated Urinary Tract Infections in Women.

Background: The Danish Holm and Cordoba Urinary Tract Infection Score (HCUTI) assessing symptom severity, bothersomeness and impact of uncomplicated urinary tract infections (uUTIs) on daily activities in women is a promising patient-reported outcome measure (PROM) for use in future research. For potential application in Germany, the present study aimed (i) to perform translation and linguistic validation of the HCUTI, and (ii) to assess content validity of the German version of the HCUTI.

Methods: Translation and linguistic validation was performed using the dual-panel method.

[Qualifications of examiners for first neonatal exam in Germany: status quo].

Midwives as well as medical doctors may carry out the initial examination of a newborn after birth in accordance with German health care regulation and guidelines. However, it is unclear which profession based on which qualification is performing these examinations in current clinical practice.The aim of the study was to assess which professions are carrying out the initial examinations of a newborn in the largest German maternity hospitals as of today.

Consensus on core domains for hand eczema trials: Signs, symptoms, control and quality of life.

Background: Hand eczema (HE) is a common and complex skin disease. A uniform set of core outcomes and related measures for use in clinical trials is lacking, making it difficult to compare results across HE studies.

Objective: To reach consensus on a set of core domains and subdomains that should be measured in future therapeutic HE trials.

Prevalence and incidence of cognitive impairment following acute respiratory distress syndrome of any cause: a systematic review and meta-analysis.

Objectives: The aim of this systematic review and meta-analysis is to synthesize and appraise the evidence on prevalence of cognitive impairment following acute respiratory distress syndrome (ARDS) of any cause.

Methods: We systematically searched PubMed, Scopus, and Web of Science for observational studies focused on cognitive impairment in adult survivors of ARDS. Risk of bias and certainty of evidence (GRADE) were assessed.

Standardizing outcomes in food allergy research: aligning clinical trials with patient priorities.

Purpose Of Review: This review explores the clinical outcomes used in immunoglobulin E (IgE)-mediated food allergy (FA) intervention studies, emphasizing unmet need for patient-centred outcomes. Standardizing outcome measurement is critical as research into FA treatments, particularly food immunotherapy, expands. Here we discuss how outcomes should reflect the multidimensional impact of FA on people's lives.

Sample size and geographical region predict effect heterogeneity in psychotherapy research for depression: a meta-epidemiological study.

Objectives: Depression is a very prevalent and burdensome disease, for which the efficacy of psychological treatments has been extensively studied in randomized controlled trials (RCTs). Meta-analytic evidence in this field is often heavily limited due to heterogeneity, meaning a broad dispersion of true treatment effects and high uncertainty when predicting future outcomes. Causes for this heterogeneity are largely unclear, and cannot be directly examined using conventional meta-analytic methods.

[Recruitment of a cohort to investigate medical follow-up care after childhood cancer: Record-Linkage between the German Childhood Cancer Registry and statutory health insurance companies (VersKiKCohort)].

The VersKiK-study is based on a record-linkage between the German Childhood Cancer Registry (GCCR) and claims data from statutory health insurances (SHI) in order to investigate the frequency of late effects and long-term medical care among pediatric cancer survivors.GCCR defined a basic population of approximately 50,000 former patients with cancer in childhood or adolescence (years of diagnosis 1991-2021) who survived until 1.1.

Disease Burden and Treatment-Seeking Behaviour of Adults with Atopic Dermatitis in Singapore: An Online Cross-Sectional Survey.

Introduction: Atopic dermatitis (AD) is a chronic systemic inflammatory skin disease with a notably high prevalence in Singapore. Despite available treatments, a significant proportion of patients remain untreated, highlighting a critical need to understand treatment-seeking behaviours and address the multi-faceted disease burden.

Methods: An online survey was conducted among 344 adult patients and caregivers answering on behalf of patients to obtain data on clinical impact and quality-of life (QoL), current treatment goals, management, financial impact and treatment-seeking behaviours.

New evidence for content validity of the German version of the Acute Cystitis Symptom Score: cognitive interview study among patients and experts.

Purpose: The Acute Cystitis Symptom Score (ACSS) is a clinically validated instrument to assess symptoms and quality of life in women with uncomplicated urinary tract infections (uUTIs). A previous study examining the content validity of the German version of the ACSS has shown some methodological limitations when rated against the criteria for content validity of the COnsensus-based Standards for the Selection of Health Measurement INstruments (COSMIN) initiative. Extending the existing evidence, the present study aimed to assess the content validity of the German version of the ACSS according to the criteria of the COSMIN methodology.

How patient-centered is the gynecological care provided for patients with genitourinary syndrome of menopause in Switzerland? A survey on the implementation of patient-centered care.

Objectives: This study assessed the extent to which patient-centered care has been implemented in patients with genitourinary syndrome of menopause.

Study Design: An online survey was developed consisting of an introduction and items covering knowledge about patient-centered care and genitourinary syndrome of menopause, inclusion criteria, biographical data, implementation of patient-centered care, competence and barriers in treating patients, treatment options in genitourinary syndrome of menopause and perceived benefit, specific dimensions of patient-centered care and the German version of the Patient-Practitioner Orientation Scale (PPOS-D12). The survey was administered to gynecologists in Switzerland.

Translating and communicating evidence on allergy prevention in children to parents: implementation study protocol.

Background: When seeking advice on allergy prevention in early childhood (Early Childhood Allergy Prevention, ECAP), parents often turn to health and social care providers, such as paediatricians, midwives, and family centres. However, these actors fulfil various, often care-related, roles, and cannot be considered 'health information providers' by default. In addition, although the scientific evidence for ECAP is often known by health professionals, it is not actively communicated.

[Mothers with migration background have significantly less knowledge of ante- and postnatal support services than mothers without migration background: cross-sectional survey in two maternity hospitals].

The aim of this study was to describe and analyse knowledge of women in childbed with and without a migration background about ante- and postnatal support services.Questionnaires were provided in 26 languages. In a cross-sectional survey, 641 women answered questions about their knowledge of 11 different regional support services, and information sources for these and other support service providers.

Healthcare Professionals' Perspectives on Sepsis Care Pathways-Qualitative Pilot Expert Interviews.

: Despite recent decades' rapid advances in the management of patients with sepsis and septic shock, global sepsis mortality and post-acute sepsis morbidity rates remain high. Our aim was, therefore, to provide a first overview of sepsis care pathways as well as barriers and supportive conditions for optimal pre-clinical, clinical, and post-acute sepsis care in Germany. : Between May and September 2023, we conducted semi-structured, video-based, one-to-one pilot expert interviews with healthcare professionals representing pre-hospital, clinical, and post-acute care settings.

[Content and quality of web-based health information for the prevention and prediction of food allergies in children: A systematic evaluation].

Introduction: Web-based health information can support health-related decisions if it is of high quality, i. e. accurate, understandable and barrier-free.

Patient-reported outcome measures for post-COVID-19 condition: a systematic review of instruments and measurement properties.

Objectives: Post-COVID-19 condition (PCC), also referred to as Long COVID, has become an emerging public health issue requiring adequate prevention, treatment and management strategies. Evaluating these strategies from the patients' perspective using patient-reported outcome measures (PROMs) is critical. In this systematic review, we aimed to critically appraise and summarise the quality of existing PROMs for PCC, and to identify PROMs that can be recommended for use in future research.