Laparoscopic repair for internal hernia associated with colostomy: a case report.

A 63-year-old woman was admitted with abdominal pain two months after laparoscopic abdominoperineal resection for rectal cancer. Computed tomography revealed dilated small intestine had passed through a defect between the lifted sigmoid colon and abdominal wall. She was diagnosed with small bowel obstruction without strangulation due to internal hernia and managed nonoperatively based on her wish.

[Effects of parental parenting attitudes on adolescents’ socialization via adolescents’ perceived parenting].

The domain-specific approach to socialization has classified socialization mechanisms into several domains, including the protection and control domains, and postulates that parent–child interactions that promote socialization in each domain are different. However, there are few empirical investigations of the domain–specific approach. This study examined whether parental parenting attitudes affected early adolescents’ empathy, including empathic concern and perspective taking, and social cognitive biases, including cognitive distortion and general beliefs about aggression, through the mediation of adolescents’ perceptions.

[The attempts and current status of cancer rehabilitation at Osaka Medical College Hospital].

We introduced an attempt at cancer rehabilitation at Osaka Medical College Hospital. We also reported trends in the clinical department that ordered the cancer rehabilitation, and the days needed to consult the rehabilitation department after hospitalization for 1,028 patients who needed rehabilitation from January to June 2012. The number of rehabilitation orders for cancer patients has increased in comparison with the same period during 2009, and the percentage of cancer rehabilitation orders has also increased, both in total and in each clinical department consulted.

Congenital cystic adenomatoid malformation in adulthood complicated by Mycobacterium celatum infection.

A 25-year-old woman with no underlying disease presented with a large fluid-filled cavitary lesion in the right lung. Mycobacterium celatum was isolated from the cavitary fluid, and treatment with ethambutol, rifampicin, and clarithromycin was initiated. After 4 months of treatment, right lower pulmonary lobectomy was performed.

EGFR tyrosine kinase inhibition worsens acute lung injury in mice with repairing airway epithelium.

Rationale: Epidermal growth factor receptor (EGFR) and its ligands play important roles in the regeneration of damaged epithelium and proliferation of various epithelial tumors. Although the EGFR-tyrosine kinase inhibitor gefitinib is effective against advanced non-small cell lung cancer with EGFR mutations, some patients treated with this agent develop severe acute interstitial pneumonia. Characteristics of patients who develop interstitial pneumonia include older age, smoking history, and preexisting interstitial pneumonia suggesting a connection between airway injury and alveolar dysfunction.

Amphiregulin attenuates bleomycin-induced pneumopathy in mice.

Amphiregulin, an EGF receptor (EGFR) ligand, is essential for epithelial development in various organs. A recent report suggested that amphiregulin acts as a protective factor in a liver injury model. Little is known about the roles of amphiregulin in lung injury and pulmonary fibrosis.

[Effects of neighborhood collective efficacy and violence on antisocial behavior: dual mediation of socialization and routine activities].

The authors examined the effects of neighborhood collective efficacy and violence on adolescents' antisocial behavior tendencies by means of the dual mediation of socialization indices (i.e., social information-processing and self regulation) and routine activities.

Involvement of mast cells in the regulation of matrix metalloproteinase-9 and tissue inhibitor of metalloproteases-1 in 12-O-tetradecanoylphorbolacetate-induced inflammation in mice.

In this study, we investigated the involvement of mast cells in the regulation of matrix metalloproteinase-9 (MMP-9) in 12-O-tetradecanoylphorbolacetate (TPA)-induced inflammation, using mast cell-deficient (W/W(v)) mice and control (+/+) mice. Topical application of TPA to the ears induced acute inflammation, accompanied by mast cell degranulation in +/+ mice, which peaked at 6-12 h. There was no significant difference in ear thickness between the groups until 12 h, but the swelling was greater in W/W(v) mice than +/+ mice at 24-36 h.