Publications by authors named "Chiduo Xu"

Background: Non-radiographic axial spondyloarthritis (nr-axSpA) is an early stage of axial spondyloarthritis characterized by the absence of definitive radiographic changes. Interleukin-17 inhibitors (IL-17i) have shown efficacy in treating nr-axSpA, but a significant proportion of patients fail to respond. Identifying predictive biomarkers for IL-17i response is crucial for optimizing treatment strategies.

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Article Synopsis
  • - The guideline aims to assist in choosing biomarkers for diagnosing and evaluating patients with axial spondyloarthritis (axSpA) through a collaboration of experts and evidence-based strategies.
  • - A total of 20 recommendations were made, including strong suggestions for HLA-B27 testing and regular monitoring of CRP/ESR, while others focused on potential biomarkers for various clinical purposes.
  • - The guideline emphasizes that healthcare professionals should consider costs, accessibility, and patient preferences when selecting tests, and it provides a toolkit of endorsed biomarkers for better clinical decision-making.
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