Paper-based SERS chip with adaptive attention neural network for pathogen identification.

High-speed and accuracy identification of pathogens has become increasingly critical in both individual patient care and public health. Artificial intelligence (AI)-assisted surface-enhanced Raman scattering (SERS) biosensors enable simultaneous identification of multiple pathogens. However, there are still problems such as low accuracy and limited diversity in bacterial fingerprints.

Implications of prenatal exposure to hyperandrogen for hippocampal neurodevelopment and autism-like behavior in offspring.

Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder that significantly jeopardizes the physical and mental well-being of children. Autism spectrum disorder results from a combination of environmental and genetic factors. Hyperandrogenic exposure during pregnancy increases their risk of developing autism.

Androgen levels in autism spectrum disorders: a systematic review and meta-analysis.

Background: Accumulating evidence suggests that the autism spectrum disorder (ASD) population exhibits altered hormone levels, including androgens. However, studies on the regulation of androgens, such as testosterone and dehydroepiandrosterone (DHEA), in relation to sex differences in individuals with ASD are limited and inconsistent. We conducted the systematic review with meta-analysis to quantitatively summarise the blood, urine, or saliva androgen data between individuals with ASD and controls.

Dissecting genetic links between Alzheimer's disease and type 2 diabetes mellitus in a systems biology way.

Alzheimer's disease (AD) and Type 2 Diabetes Mellitus (T2DM) are two of the most common diseases for older adults. Accumulating epidemiological studies suggest that T2DM is a risk factor for cognitive dysfunction in the elderly. In this study, we aimed to dissect the genetic links between the two diseases and identify potential genes contributing the most to the mechanistic link.

Proton Conductive Lanthanide-Based Metal-Organic Frameworks: Synthesis Strategies, Structural Features, and Recent Progress.

In the fields of proton exchange membrane fuel cells as well as impedance recognition, molecular sieve, and biochemistry, the development of proton conductive materials is essential. The design and preparation of the next generation of proton conductive materials-crystalline metal-organic framework (MOF) materials with high proton conductivity and excellent water stability-are facing great challenges. Due to the large radius and high positive charge of lanthanides, they often interact with organic ligands to exhibit high coordination numbers and flexible coordination configurations, resulting in the higher stability of lanthanide-based MOFs (Ln-MOFs) than their transition metal analogues, especially regarding water stability.

High Proton Conduction in Two Highly Water-Stable Lanthanide Coordination Polymers from a Triazole Multicarboxylate Ligand.

Two lanthanide coordination polymers (CPs) {[Er(Hmtbd)(Hmtbd)(HO)]·2HO} () and [Yb(Hmtbd)(Hmtbd)(HO)] () carrying an N-heterocyclic carboxylate ligand 5-(3-methylformate-1-1,2,4-triazole-1-methyl)benzen-1,3-dicarboxylate (Hmtbd) were prepared under solvothermal conditions. The single-crystal X-ray diffraction data demonstrate that and are isostructural and display 1D chain structure. Alternating current (AC) impedance measurements illustrate that the highest proton conductivities of and can attain 5.