Publications by authors named "Cheng-cheng Duan"
[Association of the polymorphism of synaptobrevins/vesicle-associated membrane proteins 8 gene with coronary heart disease in Chinese Han population].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
June 2010
Objective: To investigate the association of synaptobrevins/vesicle-associated membrane proteins 8 (VAMP8) gene rs1010 polymorphism with coronary heart disease (CHD) in Chinese Han population.
Methods: The allele and genotype frequencies of the VAMP8 gene rs1010 locus in 185 CHD patients and 149 controls were analyzed by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and DNA sequencing.
Results: There was polymorphism of the VAMP8 gene rs1010 locus in the studied population.
[Study on the correlation between CETP TaqIB, KCNE1 S38G and eNOS T-786C gene polymorphisms for predisposition and non-valvular atrial fibrillation].
Zhonghua Liu Xing Bing Xue Za Zhi
May 2008
Article Synopsis
- The study investigates the link between specific genetic polymorphisms (CETP TaqIB, KCNE1 S38G, and eNOS T-786C) and non-valvular atrial fibrillation (NVAF) in the Han population of Zhejiang province.
- Results show that the CETP B1 allele is more frequent in NVAF patients than in controls, indicating a significant association with the condition.
- Furthermore, the presence of multiple genetic polymorphisms (CETP B1, KCNE1 S38G, and eNOS T-786C) increases the risk for developing NVAF, suggesting a complex interaction among these genetic factors.