Publications by authors named "Chen-Xi Dai"
Article Synopsis
- Scientists studied how two different ways of giving mice the flu can lead to pneumonia: through their nose (intranasal) or directly into their lungs (intratracheal).
- They compared how sick the mice got by looking at their survival rates, weight changes, and how much virus was in their lungs.
- The results showed that giving the flu directly to the lungs caused worse lung damage than when it was given through the nose, making it a better method for studying serious pneumonia in mice.
The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still severe. In order to optimize the epidemic response strategy, it is urgent to evaluate the implemented prevention and control interventions (PCIs). Based on the reported data of Chongqing and Guizhou Provinces, the phased dynamic models of COVID-19 were constructed, the average intensity of the existing PCIs (from January 25 to March 2) was estimated in these two provinces.
View Article and Find Full Text PDFUnlabelled: : Several outbreaks of severe hand-foot-mouth disease (HFMD) in East Asia and Southwest Asia in recent years have had a serious impact on the countries. However, the factors that contribute to annual multiple-peak pattern of HFMD outbreaks, and how and when do these factors play the decisive role in the HFMD transmission is still unclear.
Methods: Based on the surveillance data of HFMD between 1 January 2010 to 31 December 2015 in Wenzhou, China, the daily modelfree basic reproduction number and its annual average were first estimated by incorporating incubation and infection information, then the annual model-based basic reproduction number was computed by the proposed kinetic model, and finally the potential impact factors of multiple-peak pattern are assessed through the global and time-varying sensitivity analyses.