The role of link workers in weight management for people with severe mental illness: a qualitative study.

Background: People with severe mental illness (SMI) have an increased risk of cardiovascular disease, partly due to factors such as overweight and obesity. Weight management programmes can potentially reduce this risk, but people with SMI face barriers to access and engagement.

Aim: To explore the acceptability of using link workers to address barriers to accessing and engaging with weight management programmes for people with SMI.

Compound-Specific and Intramolecular δN Analysis of a Poly-Nitrogenous Amino Acid: Histidine.

Histidine (HIS) is an essential amino acid (AA) with key physiological roles in metal chelation and proton buffering. Its three nitrogen (N) atoms─one α-amino and two in the imidazole side chain─are incorporated through distinct biosynthetic pathways and undergo different catabolic processes. Thus, its intramolecular δN values likely provide additional information on these pathways and associated N fluxes.

Wave 2 of the Multilingual Eye-Movement Corpus (MECO): New text reading data across languages.

This paper reports the Wave 2 expansion of the Multilingual Eye-Movement Corpus (MECO), a collaborative multi-lab project collecting eye-tracking data on text reading in a variety of languages. The present expansion comes with new eye-tracking data of N = 654 from 13 languages, collected in 16 labs over 15 countries, including in several languages that have little to no representation in current eye-tracking studies on reading. MECO also contains demographic, language use, and other individual differences data.

The invisible threats of sunscreen as a plastic co-pollutant: Impact of a common organic UV filter on biofilm formation and metabolic function in the nascent marine plastisphere.

Plastic debris in marine environments serves as a substrate for microbial colonisation, forming biofilms known as 'plastispheres'. Also accumulated on plastic debris are co-pollutants including UV-protective organic UV-filters from sunscreens, which likely interact with this niche through their lipophilicity. Despite their widespread use and environmental accumulation, the influence of UV-filters on plastisphere composition and function has never been investigated.

Inhibiting inflammation in adipocytes accelerates mammary tumor development in mice.

Proinflammatory signaling in adipocytes is essential for healthy adipose expansion, remodeling, and tissue integrity. We investigated the effects of targeting inflammation in either adipocytes or mammary gland epithelial cells, in the context of mammary tumor development, by locally expressing the antiinflammatory adenoviral RIDα/β protein complex in a cell type-specific manner. Suppression of adipocyte inflammation (RIDad mice) in a mammary tumor model driven by MMTV-PyMT (PyMT-RIDad mice) led to an elevated number of tumor-associated macrophages and upregulation of immunoregulatory molecules in the mammary fat pad.

Transposon-plasmid nesting enables fast response to fluctuating environments.

Mobile genetic elements (MGEs) play a critical role in shaping the response and evolution of microbial populations and communities. Despite distinct maintenance mechanisms, different types of MGEs can form nested structures. Using bioinformatics analysis of 14,338 plasmids in the NCBI RefSeq database, we found transposons to be widespread and significantly enriched on plasmids relative to chromosomes, highlighting the prevalence of transposon-plasmid nesting.

Understanding the relationship among discrimination, resource availability, health and workplace outcomes in ethnic minority nursing staff in Canada.

Purpose: Discrimination against ethnic minority nursing staff is a serious concern in healthcare and the COVID-19 pandemic has brought it to the forefront. The purpose of this survey study was to investigate the predictive relationship among discrimination experiences, resource availability, health and work outcomes among ethnic minority nursing staff during the COVID-19 pandemic.

Design/methodology/approach: A survey was conducted among ethnic minority nursing staff in Canada during the COVID-19 pandemic.

Current and Future Directions Using Virtual Avenues for Care Delivery Across the Cancer Continuum.

Oncology nurses have long been at the forefront of virtual care, transitioning from telenursing to technology-driven delivery methods that address the evolving needs of cancer patients. Initially developed to overcome barriers to care for rural and underserved populations, virtual care has grown into a critical component of oncology practice. Oncology nurses play a central role in providing timely, personalized, and holistic care, leveraging tools such as remote monitoring, patient-reported outcomes, and mHealth platforms.

New Diagnosis of Diabetes in Patients with Myocardial Infarction or Stroke: A Systematic Review and Meta-analysis.

Background: What proportion of patients with an acute myocardial infarction (MI) or stroke get a new diagnosis of diabetes (NDD) at the time of hospitalization is unclear.

Methods: We systematically searched MEDLINE and Embase from database inception to January 30, 2025, to select English-language observational studies that included adult patients with MI or stroke and reported the number of patients with NDD. The denominator was patients without diabetes.

A multiverse analysis of cleaning and analyzing procedures of eye movement data during reading.

Eye movements during reading experiments involve careful cleaning of raw data into a processed format that can then be analyzed. Through the process of cleaning and analyzing these datasets, there are many decisions that researchers make. As a result, there is a wide range of possible approaches that can be taken when analyzing datasets from reading and eye movement experiments.

Shift workers' experiences and views of sleep disturbance, fatigue and healthy behaviors: a systematic review and qualitative evidence synthesis.

Objective: Shift work is common across most societies but poses significant risks to the health of shift workers. In part, this risk is due to the disruption of healthy sleep-wake schedules. This systematic review identified qualitative research on shift workers' experiences of sleep disturbance, fatigue and healthy behaviors.

Interpersonal dyadic influences on transitions between pain states: a narrative review and synthesis.

Pain is not experienced in isolation; it is affected by and affects other people. Interactions between parents and partners and people living with pain affect beliefs, emotions and behaviours, and pain progress and change. We searched systematically for longitudinal studies of associations between specific familial, dyadic, interpersonal factors and quantitative pain transitions.

Individual differences in skilled reading and the word frequency effect.

Variation in eye movement patterns can be considerable even within skilled readers. Here, individual differences and eye movements of 88 average-to-very-skilled readers were assessed to examine the reliability of previous observations of a reduced word frequency effect associated with skilled reading. Shorter fixation durations and higher skipping rates were observed for high frequency compared to low-frequency words.

Keystone engineering enables collective range expansion in microbial communities.

Keystone engineers profoundly influence microbial communities by altering their shared environment, often by modifying key resources. Here, we show that in an antibiotic-treated microbial community, bacterial spread is controlled by keystone engineering affecting dispersal- an effect hidden in well-mixed environments. Focusing on two pathogens, non-motile Klebsiella pneumoniae and motile Pseudomonas aeruginosa, we found that both tolerate a β-lactam antibiotic, with Pseudomonas being more resilient and dominating in well-mixed cultures.

Amplitude modulation structure in French and German poetry: universal acoustic physical structures underpin different poetic rhythm structures.

French and German poetry are classically considered to utilize fundamentally different linguistic structures to create rhythmic regularity. Their metrical rhythm structures are considered poetically to be very different. However, the biophysical and neurophysiological constraints upon the speakers of these poems are highly similar.

An Evaluation of a Virtual Seminar Series for Doctor of Nursing Students to Promote Advanced Nursing Practice.

Advanced practice nurses (APNs) have been responding to worldwide changing patient comorbidities, inequalities within access to care, and a shortage of primary care physicians. The scope of practice for these nurses has been expanding internationally but varies across different jurisdictions. For a period of time during the COVID-19 pandemic, APN trainees' opportunities to work with international mentors in-person were limited.

Right ventricular free wall strain predicts transthyretin amyloidosis prognosis as well as biomarker-based staging systems.

Aims: The diagnosis of transthyretin amyloidosis (ATTR) significantly impacts the management and prognosis of patients initially presenting with heart failure (HF). Despite recent advancements in treatment, prognosticating ATTR remains challenging. In this study, we aim to assess echocardiographic parameters associated with mid-term prognosis in patients with wild-type ATTR using a biomarker staging system as a reference point.

Right atrial and right ventricular strain: prognostic value depends on the severity of tricuspid regurgitation.

Aims: Assessing right heart function is challenging, particularly when significant tricuspid regurgitation (TR) is present. Amongst available echocardiographic techniques for assessment, literatures suggest that strain imaging may be more reliable and less susceptible to loading conditions. Thus, we aimed to assess the validity of right atrial (RA) and right ventricular (RV) strain relative to conventional metrics as well as their utility in predicting patient outcomes in TR.

The jingle fallacy in comprehension tests for reading.

The Jingle fallacy is the false assumption that instruments which share the same name measure the same underlying construct. In this experiment, we focus on the comprehension subtests of the Nelson Denny Reading Test (NDRT) and the Wechsler Individual Achievement Test (WIAT-II). 91 university students read passages for comprehension whilst their eye movements were recorded.