Strategically timing land protection decisions to enhance biodiversity benefits.

Choices conservation organizations make when designing and implementing protected area strategies affect the timing of land protection. Well-timed habitat protection will have a greater impact on biodiversity outcomes; yet, decisions affecting the timing of protection have received much less attention than other aspects of protected area design. We reviewed evidence on the timing of protected area establishment and on temporal variation in factors influencing the ecological effectiveness and cost-effectiveness of establishing protected areas.

Distinct terpene metabolite blends serve as core drivers of consumer aroma preferences in fir Christmas tree species.

Real Christmas trees contribute ~$2.5 billion to the US economy annually. True fir (Abies spp.

Macroporous adsorbent resin debittering of Huang long bing (HLB)-affected orange juice and its impacts on consumer sensory acceptance.

Huang long bing (HLB) infection of oranges induces the biosynthesis and accumulation of bitter limonoids. The objective of this study was to debitter HLB-affected orange juice while preserving the tasteless and health-promoting limonoid glucoside and flavanones using resin adsorption. Three resins (FPX66, PAD900, and XAD16N) were found to have higher adsorption and desorption capacity for limonin among seven selected resins.

Cytoreduction and Hyperthermic Intrathoracic Chemotherapy for Metastatic Pseudomyxoma Peritonei.

Pleural extension of pseudomyxoma peritonei is rare, and treatment demands multidisciplinary care. Perioperative management during cytoreductive surgery and hyperthermic intrathoracic chemotherapy challenges anesthesiology and surgical teams in unique ways. Hemodynamic, arrhythmogenic, ventilatory, fluid balance, acid-base, and nephroprotection issues are important considerations.

A consumer-oriented approach to define breeding targets for molecular breeding.

Flavor is a crucial aspect of the eating experience, reflecting evolving consumer preferences for fruits with enhanced quality. Modern fruit breeding programs prioritize improving quality traits aligned with consumer tastes. However, defining fruit-quality attributes that significantly impact consumer preference is a current challenge faced by the industry and breeders.

Procedure-Focused Escape Room: A Pilot Study on Teaching High-Stakes Technical Skills in Anesthesia Residents.

Background: High-stakes yet clinically infrequent procedures are challenging to teach. Escape rooms may offer an innovative solution through game-based learning. There is limited guidance on how to design an escape room focused on physical puzzles.

A case report and anesthetic implications of situs inversus totalis in video-assisted thoracoscopic pulmonary resection.

Introduction And Importance: Reports are limited on video-assisted thoracoscopic surgery for lung malignancy of patients with situs inversus totalis (SIT). Patients with SIT have significant anatomic differences with implications that are important for surgery, anesthesia, and nursing to understand in order to provide care for this patient population.

Case Presentation: A 64-year-old man with SIT and lung adenocarcinoma needed flexible bronchoscopy and wedge resection of a 9×8 mm adenocarcinoma in the right upper lobe and underwent video-assisted thoracoscopic surgery.

Esophagectomy Enhanced Recovery After Surgery Initiative Results in Improved Outcomes.

Background: Esophagectomy for esophageal cancer is a procedure with high morbidity and mortality. This study developed a Multidisciplinary Esophagectomy Enhanced Recovery Initiative (MERIT) pathway and analyzed implementation outcomes in a single institution.

Methods: The MERIT pathway was developed as a practice optimization and quality improvement initiative.

Development and Pilot Testing of a Programmatic System for Competency Assessment in US Anesthesiology Residency Training.

Background: In 2018, a set of entrustable professional activities (EPAs) and procedural skills assessments were developed for anesthesiology training, but they did not assess all the Accreditation Council for Graduate Medical Education (ACGME) milestones. The aims of this study were to (1) remap the 2018 EPA and procedural skills assessments to the revised ACGME Anesthesiology Milestones 2.0, (2) develop new assessments that combined with the original assessments to create a system of assessment that addresses all level 1 to 4 milestones, and (3) provide evidence for the validity of the assessments.

Intrathecal Opioid Use in Kidney Transplantation: An Observational Cohort Study.

Background: Kidney transplant is the most common transplant operation performed in the United States. Although various approaches to pain management have been described, the optimal analgesic strategy remains undefined. Specifically, the role of intrathecal opioids in this patient population has not been comprehensively evaluated.

Quality characteristics and sensory evaluation of protein-rich baked snacks for adults with chronic kidney disease: a proof of concept study.

Background: Adults with chronic kidney disease (CKD) have different protein requirements than the general population. Limited protein-rich baked snack options are available for CKD adults. The purpose of this proof of concept study was to develop two protein-rich baked snacks made with whey protein isolate and soy protein isolate and to evaluate their quality characteristics and sensory perceptions for adults with CKD.

Chemical and physical properties of winter squash and their correlation with liking of their sensory attributes.

Cucurbita moschata, commonly known as squash or pumpkin, is a member of the Cucurbitaceae family originating from Central America. This species is regarded as heat tolerant and disease resistant and is commonly used in breeding programs. Calabaza (wintersquash) is an emerging market type of C.

Intraoperative Dysrhythmias Cease After Venting During Intramedullary Nailing of an Impending Femur Fracture: A Case Report.

Case: A 76-year-old woman with multiple myeloma and osteoporosis presented with right hip pain and an impending atypical femoral fracture in the setting of chronic bisphosphonate use. After preoperative medical optimization, she was scheduled for prophylactic intramedullary nail fixation. Intraoperatively, the patient experienced episodes of severe bradycardia and asystole associated with intramedullary reaming, which ceased after distal venting of the femur.

Optimal spatial evaluation of a pro rata vaccine distribution rule for COVID-19.

The COVID-19 Vaccines Global Access (COVAX) is a World Health Organization (WHO) initiative that aims for an equitable access of COVID-19 vaccines. Despite potential heterogeneous infection levels across a country, countries receiving allotments of vaccines may follow WHO's allocation guidelines and distribute vaccines based on a jurisdictions' relative population size. Utilizing economic-epidemiological modeling, we benchmark the performance of this pro rata allocation rule by comparing it to an optimal one that minimizes the economic damages and expenditures over time, including a penalty representing the social costs of deviating from the pro rata strategy.

The effect of CO2 concentration on yeast fermentation: rates, metabolic products, and yeast stress indicators.

Unlabelled: This research aimed to assess how the partial removal of carbon dioxide affects fermentations to provide a better understanding of how the manipulation of carbon dioxide concentration can be used to optimize industrial fermentations. To achieve this, fermentation kinetics, fermentation metabolic products, and yeast stress indicators were analyzed throughout ongoing brewing fermentations conducted under partial vacuum with atmospheric pressure controls. The partial vacuum reduced the solubility of carbon dioxide in the media and decreased the time necessary to reach carbon dioxide saturation.

Air temperature spikes increase bacteria presence in drinking water wells downstream of hog lagoons.

>44 million United States residents depend on private drinking water wells that are federally unregulated. Maintaining a clean groundwater supply for populations without access to public water systems is essential to supporting public health and falls to state regulators and private well owners. Yet, monitoring practices do not reflect the fact that groundwater pollution risk varies seasonally and with proximity to nearby surface-contaminated sites.

Terpene volatiles mediates the chemical basis of blueberry aroma and consumer acceptability.

Flavor is among the most important traits valued by consumers of fresh fruits. Human perception of flavor occurs primarily through two main sensory inputs, taste and aroma. Through retronasal olfaction, volatile organic compounds (VOCs) emitted by the fruit are able to produce the sensation of aroma which when combined with gustatory inputs from the tongue together underly our perception of the thousands of flavors we experience throughout our lives.

Instrumental and sensory analyses of fruit quality attributes of grafted grape tomatoes in high tunnel organic production systems.

Background: 'Vegetative' and 'generative' tomato rootstock types have been proposed based on their different effects on tomato scion growth performance; however, their impacts on fruit quality have not been characterized. No study has been conducted in which the effects of rootstock on grape tomato quality attributes were assessed using sensory and instrumental methods of evaluation. Here, we conducted two experiments to examine the influence of 'DR0141TX', 'Estamino', and 'Multifort' rootstocks (vegetative, generative, and uncharacterized, respectively) on fruit quality properties of determinate and indeterminate grape tomato scions under organic production in high tunnels, including color, size, firmness, dry matter content, soluble solids content (SSC), titratable acidity (TA), pH, and consumer sensory attributes.

There and back again; historical perspective and future directions for breeding and research studies.

The genus L. (Ericaceae) contains a wide diversity of culturally and economically important berry crop species. Consumer demand and scientific research in blueberry ( spp.

Metabolomic selection for enhanced fruit flavor.

Although they are staple foods in cuisines globally, many commercial fruit varieties have become progressively less flavorful over time. Due to the cost and difficulty associated with flavor phenotyping, breeding programs have long been challenged in selecting for this complex trait. To address this issue, we leveraged targeted metabolomics of diverse tomato and blueberry accessions and their corresponding consumer panel ratings to create statistical and machine learning models that can predict sensory perceptions of fruit flavor.

A Novel Approach to Emergency Airway Simulation Using a 3D-printed Cricothyrotomy Task Trainer.

Background: Cricothyrotomy is a final recourse for salvaging a difficult airway, yet most anesthesiology providers have little training, exposure, or comfort with the procedure. Pig tracheas are frequently used for training, but are single use and require special handling and storage. Other simulation models, such as mannequins and cadavers, are costly.

Governance structure affects transboundary disease management under alternative objectives.

Background: The development of public health policy is inextricably linked with governance structure. In our increasingly globalized world, human migration and infectious diseases often span multiple administrative jurisdictions that might have different systems of government and divergent management objectives. However, few studies have considered how the allocation of regulatory authority among jurisdictions can affect disease management outcomes.

Real-World Clinical Use and Outcomes of Telavancin for the Treatment of Bone and Joint Infections: Results from the Telavancin Observational Use Registry (TOUR™).

Background: Additional antibiotic options are needed to treat bone and joint infections caused by penicillin-resistant Gram-positive pathogens.

Objective: This subanalysis of the Telavancin Observational Use Registry (TOUR™) aimed to record real-world telavancin usage patterns in patients with bone and joint infections treated with telavancin.

Methods: TOUR was a multicenter observational-use registry study conducted at 45 US sites between January 2015 and March 2017.