DNA methylation confers a cerebellum-specific identity in non-human primates.

Selective regulation of gene expression across distinct brain regions is crucial for establishing and maintaining subdivision identities. DNA methylation, a key regulator of gene transcription, modulates transcriptional activity through the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). While DNA methylation is hypothesized to play an essential role in shaping brain identity by influencing gene expression patterns, its direct contribution, especially in primates, remains largely unexplored.

[Major Factors Influencing the Cd Content and Seasonal Dynamics in Different Land Cover Soils in a Typical Acid Rain Region].

Understanding the seasonal variations in active heavy metal components and sensitive impact factors is of importance for the ecological risk reduction during the agricultural production processes. Paddy fields, vegetable lands, and hilly forests were selected as three main land cover types to assess the seasonal characteristics of Cd bioavailability and reveal how or to what extent it was affected by the physiochemical parameters of soils, under different land-use types in a typical Cd-contaminated watershed in the middle and lower reaches of Xiangjiang River. One-year monitoring results showed that natural rainfall pH in winter and spring was lower than in summer and autumn in the study region.

[Bioavailability of Silicon Fertilizer Coupled Water Management on Soil Bioavailability and Cumulative Control of Rice in Compound Contaminated Paddy Soils].

The effect of wet irrigation (CK), agronomic measure flooding (WF), instantaneous silicon fertilizer combined with flooding measures (FYsi), mineral silicon fertilizer combined with flooding measures (FKsi), and a mix of two kinds of silicon fertilizer combined with flooding measures (FYK) on the bio-availability of As and Cd in soil and the accumulation of As and Cd in rice were investigated by pot experiments. The results showed that the pH of the soils combined with flooding measures was increased by 0.12-0.

[Effects of protein kinase C and motigen-activated protein kinase kinase/extracellular regulated protein kinases signaling pathway on mRNA level of inducible nitric oxide synthase in Tca8113 cells].

Objective: To explore the regulatory mechanism of inducible nitric oxide synthase (NOS-2) expression related to proliferation of Tca8113 cells.

Methods: RNAi mediated by short hairpin RNAs was utilized to knock down NOS-2, protein kinase C (PKC)-α, PKC-β and PKC-δ. Griess Reagent played a significant role on the detection of NO product after NOS-2 silence.

[Phytoexclusion potential studies of Si fertilization modes on rice cadmium].

The research used serious situ multi-metal contaminated soils to explore Cd repair potential in rice by adding different kinds of fertilizers, based on the outdoor pot experiment. The experiment was consisted of four treatments including non-used fertilizers (CK), the silicon fertilizer applicated into soil (Tsi), the silicon fertilizer applicated as foliar spray (Ysi) and the silicon fertilizer applicated into soil combined with the foliar spray silicon fertilizer application( Tsi + Ysi). The research examined Cd concentrations in tissues of five key growth periods to reveal cadmium (Cd) migration rules, translocation coefficients, rice biomass and yields.

[Non-point loads of soluble cadmium by in situ field experiment with different landuses, in central Hunan province mining area].

Non-point source loads of heavy metals from contaminated soil has increasingly become the major cause of heavy metal concentrations of rivers and lakes surpassed the limitation value, while only few studies had focused on quantitative monitoring of soil heavy metal transportation to water, in situ field conditions. As reported, agricultural farmland heavy metal contamination was the major contamination problem, especially for cadmium (Cd) pollution in middle and downstream of Xiangjiang River. This study selected the typical Cd polluted agricultural watershed for a case study, three typical landuse types of rice, dry farmland and unused grassland with three replicate quadrates were carried out for natural rainfall runoff hydrology processes monitoring, from 2011-2012.