Pontic Site Development Following Tooth Extraction: A Clinical Study.

This study evaluated the efficacy of alveolar ridge preservation (ARP) for pontic site development following non-molar maxillary tooth extraction versus unassisted socket healing (USH). Cone beam computed tomography was employed to measure pre-extraction facial bone thickness (FBT). An ideal baseline pontic was digitally pre-designed according to the characteristics of the site before tooth extraction, which was captured with a surface scanner.

An Emulation Model Combining Caries and Periodontitis Risk Assessment With Student Performance Report: An Exploratory Project.

Objectives: Patient risk assessments for caries and periodontitis are hourly activities for dentists. The present study tested a caries and periodontitis risk assessment format based on managing the person using a critical thinking emulation model including levels of patient capacity and disease management. Additionally, we explored factors in student analysis contributing to the designation of higher/lower-risk determinants for caries and periodontitis.

Patient self-reported perception and knowledge of periodontal disease: An observational, university-representative, survey-based analysis in an academic setting.

Background: Limited information is available about patient knowledge and perceptions of periodontal diseases. In this observational, survey-based study, the authors investigated patients' understanding of periodontal diseases and their experience after periodontal therapy using self-reported oral health-related quality of life.

Methods: Patients receiving oral health care at the College of Dentistry, University of Oklahoma, were recruited and surveyed about topics related to general knowledge, etiopathogenesis, treatment outcomes, level of treatment satisfaction, and oral health-related quality of life in the context of periodontal diseases.

Effect of Supportive Peri-implant Care After Treatment of Peri- Implant Diseases: A Systematic Review.

This PRISMA-compliant systematic review aimed to investigate the effect of supportive peri- implant care (SPIC) on peri-implant tissue health and disease recurrence following the non surgical and surgical treatment of peri-implant diseases. The protocol of this review was registered in PROSPERO (CRD42023468656). A literature search was conducted to identify investigations that fulfilled a set of pre-defined eligibility criteria based on the PICO question: what is the effect of SPIC upon peri-implant tissue stability following non-surgical and surgical interventions for the treatment of peri-implant diseases in adult human subjects? Data on SPIC (protocol, frequency, and compliance), clinical and radiographic outcomes, and other variables of interest were extracted and subsequently categorized and analyzed.

Implant surface modifications and their impact on osseointegration and peri-implant diseases through epigenetic changes: A scoping review.

Dental implant surfaces and their unique properties can interact with the surrounding oral tissues through epigenetic cues. The present scoping review provides current perspectives on surface modifications of dental implants, their impact on the osseointegration process, and the interaction between implant surface properties and epigenetics, also in peri-implant diseases. Findings of this review demonstrate the impact of innovative surface treatments on the epigenetic mechanisms of cells, showing promising results in the early stages of osseointegration.

Effect of Abutment Height on Marginal Bone Loss Around Dental Implants: A Systematic Review.

Purpose: To analyze the influence of abutment height (AH) on marginal bone loss (MBL).

Materials And Methods: A literature search was performed for human studies (RCTs, prospective and retrospective cohorts) reporting on AH and MBL. The data obtained-including clinical outcomes, treatment covariates, and patient characteristics-were analyzed.

Volumetric changes and graft stability after lateral window sinus floor augmentation: A randomized clinical trial.

Introduction: The present investigation compared the stability and volumetric changes of two different grafting material used for lateral window sinus floor augmentation (LWSFA).

Methods: Sixteen patients with a total 20 maxillary sinuses in need of LWSFA were included in the present study. The sinuses were grafted with either 100% anorganic bovine bone mineral (ABBM) alone (Group 1) or a mixture (0.

Disease Resolution Following the Treatment of Peri-implant Diseases: A Systematic Review.

The aim of this PRISMA-compliant systematic review was to analyze the evidence pertaining to disease resolution after the treatment of peri-implant diseases with the following PICO question: What is the rate of disease resolution following nonsurgical and surgical therapy for peri-implant diseases in adult human subjects? A literature search to identify studies that fulfilled preestablished eligibility criteria was conducted. Data on primary therapeutic outcomes, including treatment success and rate of disease resolution and/or recurrence, as well as a variety of secondary outcomes were extracted and categorized. A total of 54 articles were included.

The Root Complex in Posterior Teeth: A Direct Digital Analysis.

The aim of this morphometric study was to precisely determine the 3D characteristics of the root complex of the posterior dentition. Extracted and well-preserved permanent posterior teeth were included in this analysis and grouped based on tooth type and arch location. All teeth were digitally scanned.

Interproximal Soft Tissue Height Changes After Unassisted Socket Healing vs Alveolar Ridge Preservation Therapy.

The primary aim of this study was to evaluate the efficacy of alveolar ridge preservation (ARP) ther- apy compared with unassisted socket healing (USH) in attenuating interproximal soft tissue atrophy. Adult patients who underwent maxillary single-tooth extraction with or without ARP therapy were included. Surface scans were obtained and CBCT was performed to digitally assess interproximal soft tissue height changes and measure facial bone thickness (FBT), respectively.

Influence of healing time on the outcomes of alveolar ridge preservation using a collagenated bovine bone xenograft: A randomized clinical trial.

Aim: To evaluate the healing outcomes in non-molar post-extraction sockets filled with deproteinized bovine bone mineral with collagen (DBBM-C) as a function of time.

Materials And Methods: Patients in need of non-molar tooth extraction were randomly allocated into one of three groups according to the total healing time (A-3 months; B-6 months; C-9 months). The effect of alveolar ridge preservation (ARP) therapy via socket filling using DBBM-C and socket sealing with a porcine collagen matrix (CM) was assessed based on a panel of clinical, digital, histomorphometric, implant-related, and patient-reported outcomes.

Understanding the role of endotoxin tolerance in chronic inflammatory conditions and periodontal disease.

Objective: This review aims to present the current understanding of endotoxin tolerance (ET) in chronic inflammatory diseases and explores the potential connection with periodontitis.

Summary: Subsequent exposure to lipopolysaccharides (LPS) triggers ET, a phenomenon regulated by different mechanisms and pathways, including toll-like receptors (TLRs), nuclear factor kappa-light-chain enhancer of activated B-cells (NFκB), apoptosis of immune cells, epigenetics, and microRNAs (miRNAs). These mechanisms interconnect ET with chronic inflammatory diseases including periodontitis.

Influence of implant surface characteristics on the initiation, progression and treatment outcomes of peri-implantitis: A systematic review and meta-analysis based on animal model studies.

Purpose: To evaluate the impact of implant surface characteristics on the initiation, progression and treatment outcomes of peri-implantitis based exclusively on in vivo investigations.

Materials And Methods: A literature search was conducted by two independent reviewers following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to identify animal studies comparing at least two different implant surfaces affected by experimental peri-implantitis, with distinct characteristics and with or without subsequent surgical treatment that aims to arrest disease progression. The parameters evaluated included both radiographic (e.

Impact of mucosal phenotype on marginal bone levels around tissue level implants: A prospective controlled trial.

Background: The aim of this 1-year prospective clinical trial was to compare clinical parameters and marginal bone levels (MBLs) around tissue level implants with a partially smooth collar between patients with thin (≤2 mm) and thick (>2 mm) vertical mucosal phenotypes.

Methods: Thirty patients needing a single dental implant were recruited and allocated to thin (n = 14) or thick (n = 16) phenotype groups. Post-restoration, clinical (probing depth, recession, width of keratinized mucosa, bleeding on probing, suppuration, implant mobility, plaque index, and gingival index) and radiographic bone level measurements were recorded at different timepoints for 1 year.

Expression of MicroRNAs in Periodontal and Peri-Implant Diseases: A Systematic Review and Meta-Analysis.

Aim: The purpose of this review was to evaluate the expression patterns of miRNAs in periodontal and peri-implant diseases, while identifying potential miRNAs with the greatest diagnostic ability as an oral fluid biomarker.

Materials And Methods: Human and animal studies were included when evaluating expression of miRNAs between health and different forms/stages of diseases, in which microarray and/or real-time polymerase chain reaction (RT-PCR) was carried out to detect fold changes in gene expression. After full-text analysis, 43 articles were considered for a qualitative assessment, and 16 miRNAs were selected to perform meta-analysis.

Influence of keratinized mucosa on the surgical therapeutical outcomes of peri-implantitis.

Aim: To assess the impact of keratinized mucosa (KM) width around dental implants on surgical therapeutic outcomes when treating peri-implantitis.

Material And Methods: Surgically treated peri-implantitis implants were divided into two groups (KM width < 2 mm and ≥2 mm). Retrospective data were obtained after implant placement (T0) and the day of peri-implantitis surgical treatment (T1).

Characterization of macrophages infiltrating peri-implantitis lesions.

Objectives: The mechanisms involved in the initiation and progression of peri-implantitis lesions are poorly understood. It was the aim to determine the content and activation status of macrophages present in human peri-implantitis lesions and compare the current findings with the macrophage polarization associated with periodontitis lesions.

Material And Methods: A total of 14 patients were studied in this investigation.

Effects of Mechanical Instrumentation with Commercially Available Instruments Used in Supportive Peri-implant Therapy: An In Vitro Study.

Purpose: To evaluate topographic changes and effectiveness of mechanical instrumentation upon machined (MA) and roughened (RG) surfaces of dental implants.

Materials And Methods: The coronal one-third of seven RG and seven MA implants was coated with a mixture of cyanoacrylate and toluidine blue dye to resemble calculus. Implants were cleaned with three curettes (SS: stainless steel, PT: plastic, TI: titanium), two ultrasonic tips (UM: metal tip, UP: plastic tip), a titanium brush (TB), and an air-polishing device (AA) until visibly clean.

Outcomes of root resection therapy up to 16.8 years: A retrospective study in an academic setting.

Background: Root resection has been considered a viable treatment option for molars with furcation defects. However, need of a multidisciplinary approach could potentially deem this procedure less successful. The aim of the present article was to determine survival rates of root resection procedure and reasons for failure in an academic setting.

Quantitative tooth mobility evaluation based on intraoral scanner measurements.

Background: Tooth mobility assessment is subjective and current techniques require the translation of a continuous variable to a categorical variable based on the perception of the examiner. The aim of this study was to evaluate the reliability of a novel technique to assess tooth mobility.

Methods: Three experienced periodontists were asked to push tooth #16 into a buccal position to in a typodont model with different mobility (M1-M2).

Characterization of macrophage polarization in periodontal disease.

Aim: To explore the M1/M2 status of macrophage polarization from healthy, gingivitis, and periodontitis patient samples.

Materials And Methods: Gingival biopsies were collected from 42 individuals (14 gingivitis, 18 periodontitis, and 10 healthy samples) receiving periodontal therapy. Histomorphology analysis was performed with haematoxylin and eosin staining.

Dental implants-associated release of titanium particles: A systematic review.

Objectives: The presence of titanium (Ti) particles around dental implants has been reported in the literature for decades. The prospective presence of Ti debris on soft tissues surrounding dental implants has not been systematically investigated and remains to be explored. Hence, this review aimed to evaluate the origin, presence, characteristics, and location of Ti particles in relation to dental implants.

Decision Making for Management of Periimplant Diseases.

Introduction: Nonsurgical and surgical management of periimplant mucositis and periimplantitis have shown promising results in arresting periimplant marginal bone loss (MBL) and preventing implant loss. However, management of periimplant diseases still remains unpredictable for full reconstruction of lost tissues and completely arrests disease progression. The present study proposes a decision tree that compiles both clinical and radiographic presentation of failing implants to aid in the decision making for their management.

The Sinus Membrane-Maxillary Lateral Wall Complex: Histologic Description and Clinical Implications for Maxillary Sinus Floor Elevation.

Maxillary sinus floor elevation has been documented as a safe and predictable procedure for gaining vertical bone height in the atrophic posterior maxillae. Conversely, there is a lack of basic research on the characteristics of the union between the sinus membrane (SM) and the bone. Clinical implications of an impaired union in healthy or pathologic membranes remain unknown.