Publications by authors named "Carl D Mottram"
Article Synopsis
- Hepatopulmonary syndrome, affecting 10-30% of cirrhosis patients, was studied to examine its clinical impact and serum angiogenic profile in those preparing for liver transplant.
- The research involved 85 patients with hepatopulmonary syndrome and 146 without, revealing that the former had more complications, worse exercise capacity, and higher levels of certain biomarkers.
- Overall, the study found that patients with hepatopulmonary syndrome faced a significantly increased risk of death, emphasizing the condition's severity regardless of oxygenation levels.
Screening for hepatopulmonary syndrome (HPS) using pulse oximetry is recommended in liver transplant (LT) candidates because mortality is increased, independently of the severity of the oxygenation defect. LT exception points may be afforded to those with HPS and severe hypoxemia. We assessed the screening characteristics of pulse oximetry for HPS.
View Article and Find Full Text PDFBackground: Intrapulmonary vascular dilatations (IPVD) frequently are detected in patients with liver disease by the delayed appearance of microbubbles at contrast-enhanced echocardiography. IPVD with an elevated alveolar-arterial (A-a) gradient define hepatopulmonary syndrome (HPS); however, the importance of IPVD in the absence of abnormal gas exchange is unknown. We aimed to determine the clinical impact of IPVD in patients with liver disease.
View Article and Find Full Text PDFBackground: Electromyographic evaluation of diaphragmatic neuromuscular disease in patients with COPD is technically difficult and potentially high risk. Defining standard values for diaphragm thickness and thickening ratio using B-mode ultrasound may provide a simpler, safer means of evaluating these patients.
Methods: Fifty patients with a diagnosis of COPD and FEV₁ < 70% underwent B-mode ultrasound.
Care of the ventilator circuit and its relation to ventilator-associated pneumonia.
Respir Care
September 2003
Ventilator circuits should not be changed routinely for infection control purposes. The maximum duration of time that circuits can be used safely is unknown. Evidence is lacking related to ventilator-associated pneumonia (VAP) and issues of heated versus unheated circuits, type of heated humidifier, method for filling the humidifier, and technique for clearing condensate from the ventilator circuit.
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