Publications by authors named "Camilo A Duarte-Cordon"
The uterine cervix is a soft biological tissue with critical biomechanical functions in pregnancy. It is a mechanical barrier that supports the growing fetus. As pregnancy progresses, the cervix becomes more compliant and eventually opens in late pregnancy to facilitate childbirth.
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- The study examines the importance of the uterus and its biomechanical properties in supporting healthy pregnancies, identifying how alterations can lead to complications.
- Researchers analyzed the nonhuman primate (NHP) uterus at different stages of pregnancy to understand its micro-mechanical properties and composition.
- Key findings showed distinct stiffness and hydration levels in the endometrium-decidua layer, with NHP uterine properties closely resembling human data, affirming NHPs as useful models for human uterine biomechanical studies.
A successful pregnancy relies on the proper cellular, biochemical, and mechanical functions of the uterus. A comprehensive understanding of uterine mechanical properties during pregnancy is key to understanding different gynecological and obstetric disorders such as preterm birth, placenta accreta, leiomyoma, and endometriosis. This study sought to characterize the macro-scale equilibrium material behaviors of the human uterus in non-pregnancy and late pregnancy under both compressive and tensile loading.
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