Objectives: Malnutrition is a leading cause of morbidity and mortality for children under-5 globally. Low- and middle-income countries, such as Kenya, bear the greatest burden of malnutrition. The Kenyan government has been collecting clinical indicators, including on malnutrition, using District Health Information Software-2 (DHIS2) for over a decade.
View Article and Find Full Text PDFAI and robotics can facilitate humanitarian assistance and disaster response, but partnerships with practitioners are crucial.
View Article and Find Full Text PDFIn response to the COVID-19 global pandemic, recent research has proposed creating deep learning based models that use chest radiographs (CXRs) in a variety of clinical tasks to help manage the crisis. However, the size of existing datasets of CXRs from COVID-19+ patients are relatively small, and researchers often pool CXR data from multiple sources, for example, using different x-ray machines in various patient populations under different clinical scenarios. Deep learning models trained on such datasets have been shown to overfit to erroneous features instead of learning pulmonary characteristics in a phenomenon known as shortcut learning.
View Article and Find Full Text PDFRapid development of renewable energy sources, particularly solar photovoltaics (PV), is critical to mitigate climate change. As a result, India has set ambitious goals to install 500 gigawatts of solar energy capacity by 2030. Given the large footprint projected to meet renewables energy targets, the potential for land use conflicts over environmental values is high.
View Article and Find Full Text PDFThe rapid evolution of the novel coronavirus disease (COVID-19) pandemic has resulted in an urgent need for effective clinical tools to reduce transmission and manage severe illness. Numerous teams are quickly developing artificial intelligence approaches to these problems, including using deep learning to predict COVID-19 diagnosis and prognosis from chest computed tomography (CT) imaging data. In this work, we assess the value of aggregated chest CT data for COVID-19 prognosis compared to clinical metadata alone.
View Article and Find Full Text PDFAims/hypotheses: We examined the effects of milling and cooking whole grains in water to achieve starch gelatinisation on postprandial blood glucose using a randomised crossover open-label design. Participants were adults with type 2 diabetes whose body weight or medications had not changed in at least 3 months.
Methods: Postprandial blood glucose (measured as incremental AUC [iAUC]) was measured following consumption of four nutrient-matched whole-wheat porridge test-meals.
In face-to-face communication there are multiple paralinguistic and gestural features that facilitate recognition of a speaker's intended meaning, features that are lacking when people communicate digitally (e.g., texting).
View Article and Find Full Text PDFCooking is frequently associated with a healthier diet, however few youth cooking intervention studies have used control groups or follow-ups. Additionally, although cooking is associated with better mental well-being among adolescents, this has not been examined experimentally. This randomised controlled trial investigated whether a five-day intensive holiday cooking program, followed by six weeks of weekly meal kits with Facebook support groups, affected the cooking-related outcomes, diet quality and mental well-being among adolescents, with a 12-month follow-up.
View Article and Find Full Text PDFSea level rise in the United States will lead to large scale migration in the future. We propose a framework to examine future climate migration patterns using models of human migration. Our framework requires that we distinguish between historical versus climate driven migration and recognizes how the impacts of climate change can extend beyond the affected area.
View Article and Find Full Text PDFObjective: Wholegrain foods vary in the extent of processing. We investigated whether wholegrain particle size in bread influences postprandial glycemia in type 2 diabetes.
Research Design And Methods: Postprandial glycemia (incremental area under the blood glucose curve [iAUC]) was measured after consumption of three breads made with roller-milled wholegrain flour and added grains and a fourth made with stone-ground flour.
IEEE Trans Vis Comput Graph
January 2020
Deep learning is increasingly used in decision-making tasks. However, understanding how neural networks produce final predictions remains a fundamental challenge. Existing work on interpreting neural network predictions for images often focuses on explaining predictions for single images or neurons.
View Article and Find Full Text PDFThe role of cooking on health and wellbeing is a recent area of scientific interest. In order to investigate this role, a cooking program that is suitable for each target population is needed e.g.
View Article and Find Full Text PDFCompared to men, women disproportionally experience alcohol-related organ damage, including brain damage, and while men remain more likely to drink and to drink heavily, there is cause for concern because women are beginning to narrow the gender gap in alcohol use disorders. The hippocampus is a brain region that is particularly vulnerable to alcohol damage, due to cell loss and decreased neurogenesis. In the present study, we examined sex differences in hippocampal damage following binge alcohol.
View Article and Find Full Text PDFBortezomib is a first generation proteasome inhibitor that is the frontline chemotherapy for multiple myeloma with the chief dose-limiting side effect of painful peripheral neuropathy. The goal of this study was to define the behavioral phenotype in a preclinical model of bortezomib chemotherapy-induced peripheral neuropathy (CIPN) and to test whether this is matched by changes in the physiological responses of spinal wide dynamic range neurons. Sprague-Dawley rats were treated with four injections of bortezomib at four doses, 0.
View Article and Find Full Text PDFUnlabelled: Pain is ultimately a perceptual phenomenon. It is built from information gathered by specialized pain receptors in tissue, modified by spinal and supraspinal mechanisms, and integrated into a discrete sensory experience with an emotional valence in the brain. Because of this, studying intact animals allows the multidimensional nature of pain to be examined.
View Article and Find Full Text PDFUnlabelled: Spinal glial cells contribute to the development of many types of inflammatory and neuropathic pain. Here the contribution of spinal astrocytes and astrocyte gap junctions to oxaliplatin-induced mechanical hypersensitivity was explored. The expression of glial fibrillary acidic protein (GFAP) in spinal dorsal horn was significantly increased at day 7 but recovered at day 14 after oxaliplatin treatment, suggesting a transient activation of spinal astrocytes by chemotherapy.
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