Publications by authors named "Byung-Jin Park"
Chitosan nanoparticles (CNPs) were synthesized in this study to enhance the limited bioactivity and stability of grown on germinated (GRC) and effectively deliver it to target tissues. Under optimized conditions, stable encapsulation of GRC was achieved by setting the chitosan (CHI)-to-tripolyphosphate (TPP) ratio to 4:1 and adjusting the pH of TPP to 2, resulting in a zeta potential of +22.77 mV, which indicated excellent stability.
View Article and Find Full Text PDFArticle Synopsis
- GRC (germinated rice) shows anti-inflammatory, anti-allergic, and immune-regulatory effects, and this study focuses on its anti-inflammatory properties when encapsulated in chitosan nanoparticles (CN) against lung inflammation caused by particulate matter (PM).
- The optimized chitosan nanoparticles (referred to as CN6) demonstrated suitable characteristics for encapsulation, particularly with a specific GRC concentration (8 mg/mL) leading to effective entrapment and loading efficiency.
- In vivo studies on mice showed significant reductions in immune cell infiltration and lung damage from PM when treated with GRC encapsulated in CN, alongside promising results in cell culture models that indicated potential for managing PM-related inflammatory lung disease.
Fatigue is one of the common symptoms in individuals with diseases or disorders, significantly affecting quality of life (QoL) and the prognosis of diseases. This study aimed to comprehensively compare the features of fatigue across a wide range of diseases. We systematically searched the PubMed and Cochrane Library databases from inception to March 31st, 2021, and conducted a meta-analysis to generate precise estimates.
View Article and Find Full Text PDFEffectiveness of meditation for fatigue management: Insight from a comprehensive systematic review and meta-analysis.
Gen Hosp Psychiatry
December 2024
Article Synopsis
- A study found that meditation helps reduce feelings of tiredness and fatigue, making it a good option for people who have trouble sleeping.
- Researchers looked at 29 different trials involving over 4,000 participants and found that after about 9 weeks of meditation, people felt significantly less tired.
- The best results were seen in those who felt a little unhealthy and for those dealing with mental fatigue, especially when they had guidance during their practice.
Article Synopsis
- ME/CFS is a serious illness that makes people very tired, affecting about 1 out of every 100 people worldwide, and it's hard for doctors to measure how tired someone really feels.
- Researchers looked at 60 studies with over 7,000 ME/CFS patients to understand how bad their fatigue was and found that most had a fatigue level of about 78 out of 100.
- The study showed that fatigue can be different for people based on their age, the type of treatments they receive, and how their fatigue is measured.
Improvement Effects of Myelophil on Symptoms of Chronic Fatigue Syndrome in a Reserpine-Induced Mouse Model.
Int J Mol Sci
September 2021
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is associated with various symptoms, such as depression, pain, and fatigue. To date, the pathological mechanisms and therapeutics remain uncertain. The purpose of this study was to investigate the effect of myelophil (MYP), composed of and , on depression, pain, and fatigue behaviors and its underlying mechanisms.
View Article and Find Full Text PDFAssociation between Household Food Insecurity and Asthma in Korean Adults.
Int J Environ Res Public Health
June 2019
Household food insecurity has been associated with noncommunicable diseases. The aim of this study was to investigate the association between household food insecurity and asthma in Korean adults. Household food security statuses were classified into three groups: Food-secure household, food-insecure household without hunger, and food-insecure household with hunger.
View Article and Find Full Text PDFSerotonin receptor 3B polymorphisms are associated with type 2 diabetes: The Korean Genome and Epidemiology Study.
Diabetes Res Clin Pract
July 2019
Aims: Serotonin, or 5-hydroxytryptamine (5-HT), and serotonin receptor (HTR) subtypes contribute to controlling energy homeostasis. We investigated the association of polymorphisms of serotonin related genes with type 2 diabetes in Korean adults using a community-based prospective cohort study.
Methods: A total of 8840 participants (4205 Ansung, 4635 Ansan) from the Korean Genome and Epidemiology Study (KoGES)-Ansan and Ansung were included.
Patients with coronary artery calcification have an increased risk of coronary vascular events and mortality. Coronary artery calcification can be quantified using the coronary calcium score (CCS) from multi-detected row computed tomography (MDCT), and the score is proportionally related to the severity of atherosclerotic disease. Mean platelet volume (MPV) is gaining interest as a new independent cardiovascular risk factor.
View Article and Find Full Text PDF