Chem Biodivers
July 2025
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are difficult to treat due to its resistance profile and the scarcity of new antibiotics, necessitating alternative therapeutic strategies. This study explores the antibacterial, antivirulence, and in vivo effects of Algrizea minor essential oil (EOAM) against MRSA isolates. Chemical analysis identified β-pinene (38.
View Article and Find Full Text PDFhas long been used in Latin American folk medicine for the treatment of respiratory and gastrointestinal disorders. Therefore, toxicological and phytochemical investigations are required to assess the safety and support the evidence-based use of its bark in medicinal applications. This study aimed to evaluate the aqueous bark extract of , focusing on its chemical composition and its antioxidant, cytotoxic, and genotoxic properties.
View Article and Find Full Text PDFAppl Biochem Biotechnol
July 2025
The aim of the study was to extract and characterize collagen from solid untanned skin waste from the processing of leather in a Capra aegagrus tannery. Using pepsin (SPC), 37 g of collagen were obtained from 100 g of dry weight skin. Characterization took place using SDS-PAGE, FTIR and UV absorption techniques, identifying it as type I collagen.
View Article and Find Full Text PDFMolecules
December 2024
is a vector responsible for the transmission of various arboviruses and is considered by the World Health Organization to be one of the main public health problems in the world. This study evaluated the larvicidal and oviposition activity of essential oils from , and and their formulations. Chromatographic analysis by GCMS identified a total of 28, 52 and 18 compounds for the oils of the species , and , respectively.
View Article and Find Full Text PDFInflammopharmacology
October 2024
Eugenia flavescens is a species cultivated in Brazil for food purposes. Given the potential application of essential oils from plants of the genus Eugenia, this study was carried out to investigate the chemical composition, acute toxicity, antioxidant, antinociceptive, gastroprotective activities, and possible mechanisms of action of the essential oil from the leaves of E. flavescens (EOEf).
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Ethnopharmacological Relevance: Species of the Jatropha genus (Euphorbiaceae) are used indiscriminately in traditional medicine to treat accidents involving venomous animals. Jatropha mutabilis Baill., popularly known as "pinhão-de-seda," is found in the semi-arid region of Northeastern Brazil.
View Article and Find Full Text PDFAquat Toxicol
June 2024
Numerous studies evaluate chemical contaminants released by human activities and their effects on biota and aquatic ecosystems. However, few of these studies address non-toxic agents and their potentially harmful effects, which, in a concealed manner, culminate in an increased ecotoxicological risk for aquatic life and public health. This study investigated the presence of toxic and non-toxic pollutants in one of the main watersheds in Northeast Brazil (Rio São Francisco) and proposed a model of dispersion and transfer of resistance among the analyzed bacteria, also assessing the health risks of individuals and aquatic organisms present there.
View Article and Find Full Text PDFNat Prod Res
April 2024
This work aimed to investigate the chemical composition, antioxidant capacity, antibacterial activity, and intestinal and gastric protective effects, in addition to the acute toxicity of the essential oil of (EOEs). ()-caryophyllene (18.01%), β-pinene (8.
View Article and Find Full Text PDFChem Biodivers
November 2023
Bacteria are associated with many infections that affect humans and present antibiotic resistance mechanisms, causing problems in health organisations and increased mortality rates. Therefore, it is necessary to find new antibacterial agents that can be used in the treatment of these microorganisms. Geopropolis is a natural product from stingless bees, formed by a mixture of plant resins, salivary secretions, wax and soil particles, the chemical composition of this natural product is diverse.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2023
J Ethnopharmacol
March 2023
Ethnopharmacological Relevance: Eugenia gracillima is widely used by the population in the manufacture of pulps and jellies, with popular reports of its use in the treatment of infections in the urinary system, respiratory and dermatological problems. A previous study reports that EO from E. gracillima leaves proved to be a promising antioxidant agent in combating the promastigote forms of protozoa.
View Article and Find Full Text PDFInflammopharmacology
December 2022
Eugenia pohliana DC.(Myrtaceae) is used in folk medicine by communities in Brazil. However, there are no reports on its biological activity.
View Article and Find Full Text PDFJ Sci Food Agric
January 2023
Background: Food processing produces large volumes of waste that can be transformed into useful and relevant ingredients. The by-product of oil extraction from faveleira seeds is a potentially low-cost raw material that can be used for obtaining functional foods. This study aimed to analyze the physicochemical properties, chemical composition, and antioxidant activity of faveleira (Cnidoscolus quercifolius Pohl) seed press cake flour (FSPCF).
View Article and Find Full Text PDFThis study investigated the gastroprotective effect of TA against gastric ulcer in mice, and its possible mechanisms of action. The effects were investigated in a model of ethanol and ethanol/HCl induced ulcers, and physical barrier test. Quantification of oxidative stress mediators and inflammatory cytokines in gastric tissue was performed.
View Article and Find Full Text PDFComp Biochem Physiol C Toxicol Pharmacol
March 2021
The search for new therapies, derived from natural compounds in order to prevent and treat Parkinson's disease (PD) has aroused the interest of many researchers. Spondias mombin (L) has active constituents with known antioxidant and anti-inflammatory activities. The aim of this study was to evaluate the neuroprotective potential of the hexane extract of S.
View Article and Find Full Text PDFNat Prod Res
May 2022
is a tree species of the Brazilian Caatinga biome. This paper is the first report on the chemical composition and the antimicrobial and antivirulence activities of essential oil extracted from its leaves. The oil was extracted by hydrodistillation.
View Article and Find Full Text PDFThe Croton argyrophyllus leaf essential oil has anti-inflammatory, antioxidant, cytotoxic among other activities. However, there are chemical composition variations in the literature. This work reports the first study of the intraspecific chemical variation of C.
View Article and Find Full Text PDFJ Ethnopharmacol
January 2021
Ethnopharmacological Relevance: Verbesina macrophylla (Cass.) S.F.
View Article and Find Full Text PDFFood Chem
February 2021
Faveleira (Cnidoscolus quercifolius) is an emerging Brazilian plant, with seeds rich in edible oil. This study investigates physicochemical properties, chemical composition, thermal and oxidative stability, in vitro and in vivo toxicity, antioxidant, antinociceptive and anti-inflammatory activities of faveleira seed oil. It was observed that the oil has low acidity, value of peroxide, chlorophyll, carotenoids, β-carotene and high concentrations of unsaturated fatty acids.
View Article and Find Full Text PDFNat Prod Res
November 2021
This work aimed to investigate the chemical composition, antimicrobial activity, synergistic effect, and structure changes of the essential oil of (EOHr). Forty-five constituents were identified in the essential oil, corresponding to 94.43% of the compounds present, being the main components E-Caryophyllene (36.
View Article and Find Full Text PDFJ Ethnopharmacol
January 2020
Ethnopharmacological Relevance: Hymenaea cangaceira Pinto, Mansano & Azevedo (Fabaceae) is a Brazilian medicinal plant widely known as "Jatobá". In folk medicine, it is used to treat infections, respiratory problems, rheumatism, antitumoral, inflammation and pain, however, no activity has been scientifically validated.
Aim Of The Study: This study investigated chemical composition of essential oil from Hymenaea cangaceira (EOHc), antimicrobial, antinociceptive and antioxidant activities besides protection against DNA damage and hemolysis.
Nat Prod Res
October 2020
A salt-tolerant cellulase secreted by a marine sp. SR22 strain with wide resistance to temperature and pH was purified and characterized. Its approximate mass was 37 kDa.
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