As new alloys are being developed for additive manufacturing (AM) applications, questions related to the temperature-dependent structural and compositional stability of these alloys remain. In this work, the benefits and limitations of a unique method for testing this stability are presented. This system employs the use of polychromatic synchrotron light to perform energy-dispersive x-ray diffraction (ED-XRD) on an electrostatically levitated sample at high temperatures.
View Article and Find Full Text PDFPurpose: We investigated the influence of passive arm-support exoskeleton (ASE) with different levels of torque (50, 75, and 100%) on upper arm osteokinematics.
Methods: Twenty participants completed a cyclic overhead drilling task with and without ASE. Task duration, joint angles, and angular acceleration peaks were analyzed during ascent and descent phases of the dominant upper arm.
The relationships between materials processing and structure can vary between terrestrial and reduced gravity environments. As one case study, we compare the nonequilibrium melt processing of a rare-earth titanate, nominally 83TiO-17NdO, and the structure of its glassy and crystalline products. Density and thermal expansion for the liquid, supercooled liquid, and glass are measured over 300-1850 °C using the Electrostatic Levitation Furnace (ELF) in microgravity, and two replicate density measurements were reproducible to within 0.
View Article and Find Full Text PDFA source of support during birth could be the solution to negative outcomes for the mother and her baby. To improve the birthing experience and increase positive birthing outcomes, sources of support during pregnancy should be evaluated and understood. The goal of this review was to synthesize the existing literature on how doulas might improve birth outcomes.
View Article and Find Full Text PDFJ Pediatr Pharmacol Ther
June 2023
Objective: Pediatric hypertension affects 2% to 5% of children and adolescents in the United States and is frequently undertreated. The increasing prevalence of pediatric hypertension and worsening physician shortage create difficulties in closing this treatment gap. Physician-pharmacist collaborations have been shown to improve patient outcomes in adult patients.
View Article and Find Full Text PDFThe dynamics of levitated liquid droplets can be used to measure their thermophysical properties by correlating the frequencies at which normal modes of oscillation most strongly resonate when subject to an external oscillatory force. In two preliminary works, it was shown via electrostatic levitation and processing of various metals and alloys that (1) the resonance of the first principal mode of oscillation (mode n = 2) can be used to accurately measure surface tension and (2) that so-called "higher-order resonance" of n = 3 is observable at a predictable frequency. It was also shown, in the context of future space-based experimentation on the Electrostatic Levitation Furnace (ELF), a setup on the International Space Station (ISS) operated by Japan Aerospace Exploration Agency (JAXA), that while the shadow array method in which droplet behavior is visualized would be challenging to identify the n = 3 resonance, the normal mode n = 4 was predicted to be more easily identifiable.
View Article and Find Full Text PDFBackground: Rotator cuff tear (RCT) chronicity is an important factor in considering treatment options and outcomes for surgical repair. Many factors may contribute to delayed treatment, including timely access to care due to insurance status. The purpose of this study was to evaluate the relationship between the magnitude of RCT on presentation and insurance status.
View Article and Find Full Text PDFObesity is associated with lipid droplet (LD) accumulation, dysregulated lipolysis and chronic inflammation. Previously, the caspase recruitment domain-containing protein 9 (CARD9) has been identified as a potential contributor to obesity-associated abnormalities including cardiac dysfunction. In the current study, we explored a positive feedback signalling cycle of dysregulated lipolysis, CARD9-associated inflammation, impaired lipophagy and excessive LD accumulation in sustaining the chronic inflammation associated with obesity.
View Article and Find Full Text PDFPrevious studies reported that adolescents with a sport-related concussion history showed prolonged visuomotor deficits during an eye-hand decoupling task until around 1.5-2 years post-event. The present study expands this work, examining whether such deficits do or do not emerge when testing individuals in young adulthood, i.
View Article and Find Full Text PDFThe present study expands previous work that reported eye-hand decoupling (EHD) deficits in young adults with concussion history from adolescence. Here, we examine whether these deficits in movement planning (i.e.
View Article and Find Full Text PDFVarious cardiopulmonary pathologies associated with electronic cigarette (EC) vaping have been reported. This study investigated the differential adverse effects of heating-associated by-products versus the intact components of EC aerosol to the lungs and heart of mice. We further dissected the roles of caspase recruitment domain-containing protein 9 (CARD9)-associated innate immune response and NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome in EC exposure-induced cardiopulmonary injury.
View Article and Find Full Text PDFAdditive Friction Stir-Deposition (AFS-D) is a transformative, metallic additive manufacturing (AM) process capable of producing near-net shape components with a wide variety of material systems. The solid-state nature of the process permits many of these materials to be successfully deposited without the deleterious phase and thermally activated defects commonly observed in other metallic AM technologies. This work is the first to investigate the as-deposited microstructure and mechanical performance of a free-standing AA5083 deposition.
View Article and Find Full Text PDFExp Brain Res
August 2021
Visually guided reaching precision and accuracy depend on the level of coupling between movements of the eyes and hand. In the present study, participants performed central fixations and either saccadic or smooth pursuit eye movements during fast and accurate reaching tasks involving eye-hand coupling and decoupling to better understand type of eye movement influence over upper limb control. Some eye-hand coupling and decoupling tasks also included hand reversals, where the hand moves away from the target to direct a cursor toward the target to account for various levels of hand-cursor and eye-cursor coupling.
View Article and Find Full Text PDFMagnetic skyrmions are topologically stable vortex-like spin structures that are promising for next generation information storage applications. Materials that host magnetic skyrmions, such as MnSi and FeGe with the noncentrosymmetric cubic B20 crystal structure, have been shown to stabilize skyrmions upon nanostructuring. Here, we report a chemical vapor deposition method to selectively grow nanowires (NWs) of cubic FeGe out of three possible FeGe polymorphs for the first time using finely ground particles of cubic FeGe as seeds.
View Article and Find Full Text PDFPurpose: To report an unusual case of hydroxychloroquine toxicity after short-term therapy.
Methods: Observational case report.
Results: A 56-year-old woman presented to the Ophthalmology Clinic at Walter Reed Army Medical Center (WRAMC) with a 6-month history of gradually decreasing vision in both eyes.
Nodular fasciitis (NF) is a benign proliferation of fibroblasts and myofibroblasts that rarely occurs in the periorbital region. We report what we believe to be the first case of periorbital NF associated with pregnancy. A case of intravascular fasciitis, a NF variant, has been reported during pregnancy, but it was not located in the periorbital region.
View Article and Find Full Text PDFCongenit Heart Dis
February 2014
Objective: Long QT syndrome (LQTS) is a cardiac channelopathy predisposing to syncope and sudden death secondary to LQT-triggered ventricular arrhythmias. Long QT syndrome has been regarded as a purely electrical disease. Recent reports have shown by echocardiography that LQTS patients have contraction abnormalities that are associated with cardiac arrhythmias.
View Article and Find Full Text PDFPurpose: To describe the macular findings after closed globe ocular injuries sustained from blasts.
Methods: A retrospective chart review from February 2003 to March 2010 of all soldiers with closed globe ocular injuries sustained during combat with macular findings of trauma on examination was completed.
Results: There were 36 eyes that met the inclusion criteria.
Objective: We sought to identify complications that occurred during congenital cardiac catheterization (CCC) and determine factors that could improve the quality of care provided to patients with congenital heart disease during this procedure.
Design: We reviewed the electronic medical record for 903 CCC cases, (455 female; mean age = 29 +/- 22 years, range = birth to 91 years) performed in our catheterization laboratory from 2005 to 2007. Included in this cohort are 342 cases performed on patients less than 18 years of age.
J Ophthalmic Inflamm Infect
December 2010
Purpose: The purpose of this study is to elicit the role of oral low-dose sirolimus as a corticosteriod-sparing agent for active uveitis.
Methods: A retrospective, interventional case series was performed by reviewing the clinical records of all patients treated with oral, low-dose sirolimus (1-4 mg daily) for severe uveitis. Data reviewed included symptomatic improvement, Snellen best-corrected visual acuity, corticosteroid requirement, sirolimus levels, intraocular inflammation, spectral-domain optical coherence tomography, and fluorescein angiogram.