Publications by authors named "Ben G Cooper"
Motile Living Biobots Self-Construct from Adult Human Somatic Progenitor Seed Cells.
Adv Sci (Weinh)
January 2024
Article Synopsis
- Fundamental knowledge gaps exist regarding how adult human cells can change and what kinds of shapes and behaviors these genetically normal cells can exhibit when turned into living constructs called anthrobots.
- Anthrobots are bio-robots derived from human lung cells that can form into small spheroid shapes (30-500 microns) and move using cilia, showing diverse behaviors including various movement patterns and speeds.
- These anthrobots can repair damaged human neural cell sheets in lab settings, and their different shapes and structures are linked to their movement types, highlighting the potential of manipulating their environments to discover new biological functions without altering their genetic material directly.
All living cells maintain a charge distribution across their cell membrane (membrane potential) by carefully controlled ion fluxes. These bioelectric signals regulate cell behavior (such as migration, proliferation, differentiation) as well as higher-level tissue and organ patterning. Thus, voltage gradients represent an important parameter for diagnostics as well as a promising target for therapeutic interventions in birth defects, injury, and cancer.
View Article and Find Full Text PDFIn this direct replication of Mueller and Oppenheimer's (2014) Study 1, participants watched a lecture while taking notes with a laptop ( = 74) or longhand ( = 68). After a brief distraction and without the opportunity to study, they took a quiz. As in the original study, laptop participants took notes containing more words spoken verbatim by the lecturer and more words overall than did longhand participants.
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