Publications by authors named "Behvar Asghari"

This research focused on improving the drought tolerance of Dracocephalum moldavica, a plant vulnerable to water stress, by exploring the combined effects of melatonin spray and mycorrhizal fungus Glomus intraradices inoculation. The experiment was designed as a factorial randomized study to evaluate the plant's morphological, physiological, and phytochemical responses under different drought conditions (100%, 75%, and 50% field capacity). The findings revealed that the combination of melatonin and mycorrhizal inoculation significantly improved the morphological traits of Moldavian balm under drought conditions.

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Green synthesis, an approach that has gained widespread recognition in recent years due to environmental and health concerns, was employed to synthesize green zinc oxide nanoparticles (G-ZnO NPs) using a hydro-alcoholic extract derived from dried damask rose petals. The synthesized nanoparticles were confirmed using an X-ray diffractometer, UV-visible, and Fourier transform infrared spectrometry. A morphological examination with a field emission scanning electron microscope revealed that the G-ZnO NPs had a diameter ranging from 44.

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Article Synopsis
  • Silver nanoparticles (AgNPs) were synthesized using dandelion flower extract, with an average size of 45-55 nm, and characterized using various techniques (FTIR, XRD, UV-visible, SEM, EDX).
  • G-AgNPs demonstrated superior antioxidant (47.8% radical scavenging), antimicrobial (effective against E. coli and S. aureus), and photocatalytic (75.22% inhibition of methylene blue dye) properties compared to commercially available AgNPs of different sizes (20 nm and 80-100 nm).
  • Additionally, G-AgNPs showed significant α-glucosidase inhibition (88.37%), outperforming the commercial variants (61.7% and 50
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A simple, efficient and green approach for the synthesis of spiro-dihydropyridines derivatives by one-pot multi-component reaction of isatin or acenaphthoquinone derivatives (1 equiv) with malononitrile (1 equiv) and N,N'-substituted-2-nitroethene-1,1-diamines (1 equiv) in PEG-400 under catalyst-free conditions is described. This method provides several advantages such as environmental friendliness, short reaction time, and simple workup procedure for the synthesis of biologically important compounds. The ability of synthesized compounds in inhibition of acetyl and butyrylcholinesterase were investigated both in vitro and in silico.

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  • Researchers synthesized new benzimidazole and pyrimidine derivatives from amino acids using phosphorus oxychloride, achieving high yield and purity.
  • The compounds were identified using various spectroscopic methods and tested for their ability to inhibit α-glucosidases from yeast and rats.
  • Notably, benzimidazole derivatives 4c and 4d, as well as pyrimidine derivatives 5c and 5d, showed significant inhibition, with the most potent inhibitors having low IC50 values, indicating strong potential as antihyperglycemic agents.
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It is believed that the inhibition of carbohydrate hydrolyzing enzymes including α-amylase and α-glucosidase is one of the therapeutic approaches to decrease the postprandial glucose level after a meal, especially in the people with type 2 diabetes. Medicinal plants and their extracts are one of the main sources to find new inhibitors to the enzymes. In our study four flavonoids, namely luteolin 7-O-glucoside (1), luteolin 7-O-glucuronide (2), diosmetin 7-O-glucuronide (3) and salvigenin (4) were isolated from aerial parts of Salvia chloroleuca.

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The composition and in vitro antibacterial activity of essential oils from four Satureja species (S. bachtiarica, S. khuzistanica, S.

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In this paper multivariate response surface methodology (RSM) has been used for the optimization of hydrodistillation-headspace solvent microextraction (HD-HSME) of thymol and carvacrol in Thymus transcaspicus. Quantitative determination of compounds of interest was performed simultaneously using gas chromatography coupled with flame ionization detector (GC-FID). Parameters affecting the extraction efficiency were assessed and the optimized values were 5 min, 2 microL and 3 min for the extraction time, micro-drop volume and cooling time after extraction, respectively.

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  • A study analyzed the essential oils from three types of sage plants (Salvia multicaulis, S. sclarea, and S. verticillata) collected at peak bloom using hydrodistillation and advanced gas chromatography techniques.
  • The essential oils were tested for antimicrobial effects against various bacteria and fungi, showing moderate to high antibacterial activity against most bacteria except for Pseudomonas aeruginosa, which was resistant.
  • Antifungal activity was minimal, with only the oil from S. multicaulis exhibiting slight effectiveness against two yeast strains (Candida albicans and Saccharomyces cerevisiae).
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