Quasi-Solid-State ECL Immunosensor Based on Adenine-Incorporated MOFs Adsorption and Electrochemical Release of Ru(bpy) for Signal Enhancement.

Electrochemiluminescence (ECL) immunosensors are widely used for cancer marker detection due to their high selectivity, but their reuse is limited by the need for electrode reconditioning after each assay, hindering large-scale application. In our work, a novel quasi-solid-state ECL immunosensor is designed. A gel-cast cellulose membrane is used as our sensor platform, providing a new location for biomolecular-specific identification.