Publications by authors named "Austin V Cheng"
Rapid pacing and high-frequency jet ventilation additively improve catheter stability during atrial fibrillation ablation.
J Cardiovasc Electrophysiol
July 2020
Article Synopsis
- Atrial fibrillation ablation success depends on catheter stability, which can be enhanced by rapid cardiac pacing and high-frequency jet ventilation (HFJV).
- In a study with 40 patients, the combination of rapid pacing and HFJV significantly reduced variability in contact force during ablation compared to pacing or HFJV alone.
- The findings indicate that using both techniques together leads to better catheter stability, potentially improving the outcomes of atrial fibrillation ablation procedures.
Utilization of a Radiation Safety Time-Out Reduces Radiation Exposure During Electrophysiology Procedures.
JACC Clin Electrophysiol
May 2019
Article Synopsis
- * Data was collected before and after implementing the time-out in a lab, showing a 21% reduction in radiation exposure levels for patients and healthcare professionals.
- * The findings support adopting radiation safety time-outs in electrophysiology and other fluoroscopy-dependent medical practices to enhance safety and minimize radiation risks.
Article Synopsis
- - The study aimed to explore how pacing-induced heart rate changes affect catheter-tissue contact and impedance reduction during radiofrequency ablation procedures for atrial fibrillation (AF) in patients.
- - Results indicated that pacing significantly decreased the variability of catheter-tissue contact and led to a 30% greater reduction in tissue impedance, suggesting more effective ablation.
- - The findings suggest that manipulating heart rate can improve catheter performance and lesion quality, offering a new strategy for optimizing AF ablation outcomes.
The use of bone marrow-derived mesenchymal stromal cells (BMSC) in the treatment of alloimmune and autoimmune conditions has generated much interest, yet an understanding of the therapeutic mechanism remains elusive. We therefore explored immune modulation by a clinical-grade BMSC product in a model of human-into-mouse xenogeneic graft-versus-host disease (x-GVHD) mediated by human CD4(+) Th1 cells. BMSC reversed established, lethal x-GVHD through marked inhibition of Th1 cell effector function.
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