Radiofrequency thermocoagulation with glycerin rhizotomy compared with glycerin rhizotomy alone for pain improvement in repeat rhizotomy.

Objective: Because of the frequent recurrence of pain for patients with trigeminal neuralgia (TN), many undergo repeat percutaneous rhizotomy. The aim of this study was to assess whether the use of radiofrequency thermocoagulation with glycerin rhizotomy (RFTC-GR) or GR alone in repeat rhizotomy procedures influences postoperative pain and numbness outcomes.

Methods: The electronic medical records of 465 patients with TN who underwent repeat rhizotomy at the authors' institution between 2011 and 2022 were reviewed.

The role of extent of resection, chemoradiation, and MGMT promoter methylation in overall survival in a large cohort of IDH-wildtype glioblastoma.

Objective: Although MGMT promoter methylation, gross-total resection (GTR), and adjuvant chemoradiation therapy are known to independently improve clinical outcomes for patients with glioblastoma (GBM), their combined influence remains unclear. In the present study, the authors investigated the complementary role of these factors in GBM prognosis.

Methods: The 2022 National Cancer Database was queried for individuals with histologically confirmed IDH-wildtype GBM WHO grade 4 and available MGMT promoter methylation status data.

Prevalence, therapeutic approaches, and survival rates of brain metastases in non-small cell lung cancer: a multi-institutional claims-based study from 2014 to 2024.

Purpose: Brain metastases (BM) cause substantial morbidity and mortality in patients with non-small cell lung cancer (NSCLC). Updated epidemiological studies are crucial to guide screening and treatment strategies. We investigated the prevalence, timing, and outcomes of BM in patients diagnosed with NSCLC utilizing the TrinetX Oncology database.

Repeat percutaneous rhizotomy for trigeminal neuralgia is not associated with an increased risk of postoperative complications.

Background And Objectives: Patients undergoing percutaneous rhizotomy for trigeminal neuralgia (TN) may require several procedures to manage their pain. However, it is not fully understood whether repeat procedures influence postoperative complication rates.

Methods: We retrospectively reviewed patients undergoing rhizotomy at our institution from 2011 to 2022.