SAGE Open Med Case Rep
August 2025
In dental practice, impacted canines are common clinical conditions that compromise tooth mobility, thereby severely affecting functionality and esthetics. They also represent a significant challenge, particularly when associated with odontogenic pathologies such as dentigerous cysts and odontomas. These entities, despite benign, can cause complications, including tooth displacement, root resorption, and alterations in normal eruption, compromising both esthetics and function.
View Article and Find Full Text PDFComplex geometries achievable with resin-based 3D printing are susceptible to lower levels of surface roughness, particularly in areas where support structures are attached and removed. The slicing parameter serves as the cornerstone for developing a model for predicting the corresponding output. In the present research, a resin 3D printer is used to fabricate the specimens in accordance with the combination of important parameters that were recovered utilizing the design of the experiment (DoE).
View Article and Find Full Text PDFPeriodontitis and viral liver infections, particularly hepatitis B virus (HBV) and hepatitis C virus (HCV), are chronic inflammatory conditions with a high prevalence worldwide. Recent evidence establishes a possible bidirectional relationship between the two, based on shared immunological, microbial, and inflammatory mechanisms. The objective of this study was to analyze and synthesize the scientific literature on the interactions between viral hepatitis and periodontal health.
View Article and Find Full Text PDFBackground And Aims: Dental anxiety in children is a prevalent concern that affects compliance and treatment outcomes in pediatric dentistry. Nonpharmacological behavioral interventions (NPBI), including virtual reality (VR) and tell-show-do (TSD), are commonly used to manage dental anxiety. This systematic review and meta-analysis aim to evaluate the effectiveness of these interventions in reducing anxiety and pain perception in pediatric dental patients.
View Article and Find Full Text PDFClin Med Insights Pediatr
August 2025
Objective: The objective of this study was to assess the risk of dental caries in relation to fingerprint patterns in children with hearing impairment.
Methods: This study involved 373 children selected from 3 different schools of children with hearing impairment. Dental caries status was recorded using the DMFT index.
Objectives: Bone repair and regeneration are important processes for treating bone defects and injuries. However, traditional bone grafts like autografts and allografts have limitations, such as complications at the donor site and immune rejection. As a result, there is growing interest in using polylactic acid (PLA), a biodegradable and biocompatible material, as a synthetic bone substitute.
View Article and Find Full Text PDFObjectives: The study aimed to evaluate the significant trends of advancement in the body of literature of specialty journals on molecular biological investigations of ameloblastoma (AB). Additionally, this bibliometric study sought to identify the authors, organizations, journals, and countries from emerging regions that have exerted the most significant influence on molecular biological and bioinformatics studies on AB.
Novelty Of Study: The novelty of this study lies in its comprehensive bibliometric integration of bioinformatics and molecular perspectives, offering a structured roadmap for future ameloblastoma research.
Background: Enhancing oral health-related quality of life requires oral health knowledge. Mobile healthcare increases assistance and healthcare through mobile devices and wireless technologies. Using information and technology, eHealth enhances healthcare services by enabling digital administration and improving data interchange and coordination among providers, but its influence on oral health knowledge and practice is unclear.
View Article and Find Full Text PDFObjectives: The present systematic review and meta-analysis aimed to compare the efficacy of three-dimensional (3D) imaging techniques in terms of accuracy and precision for periodontal disease assessment.
Material And Methods: A literature search was conducted across multiple databases (PubMed, Scopus, Web of Science, Google Scholar, and ScienceDirect) following Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) protocols. The primary outcomes focused on comparing the accuracy and precision of 3D versus two-dimensional (2D) imaging techniques.
J Clin Lab Anal
August 2025
Background: Activation of the IL-23/IL-17 cytokine axis could trigger peri-implant bone loss. The aim of this review was to analyze whether in people with peri-implantitis (PI) and peri-implant mucositis (PM) the concentrations of the interleukin-23 and interleukin-17 in peri-implant crevicular fluid (PICF) are elevated compared to people with healthy dental implants (HDI).
Methodology: The protocol of this study was registered in OSF (ID: 10.
Background: Temporomandibular disorders (TMD) are multifactorial conditions that involve pain, dysfunction, and impaired jaw movement, significantly impacting patients' quality of life. Emerging evidence suggests that psychological factors, including anxiety, depression, and stress, play a crucial role in the onset and progression of TMD. However, the exact nature of this relationship remains unclear.
View Article and Find Full Text PDFOral squamous cell carcinoma (OSCC) is a malignant neoplasm with high mortality and recurrence. Its etiology is multifactorial and involves environmental factors such as smoking, alcohol, and human papilloma virus infection, as well as genetic factors such as single nucleotide polymorphisms. The / axis is key in the regulation of cell apoptosis, proliferation, migration, and invasion, which are fundamental processes in cancer development.
View Article and Find Full Text PDFInt J Inflam
May 2025
Toll-like receptors (TLR2 and TLR4) are crucial in the detection of pathogen-associated molecular patterns (PAMPs) during periodontitis, resulting in exacerbated production of proinflammatory cytokines and ultimately tissue damage and bone loss associated with this periodontal disease. This systematic review and meta-analysis aimed to systematically analyze and quantify the differences between TLR2 and TLR4 levels in the saliva and plasma of individuals with chronic periodontitis (CP) and systemically and periodontally healthy subjects (SPHS). The databases consulted were Scopus, Web of Science, and PubMed from 2011 to 2024 to locate cross-sectional studies that measured TLR2 and TLR4 levels.
View Article and Find Full Text PDFMonocyte chemoattractant protein 1 (MCP-1) is involved in monocyte chemotaxis, endothelial activation and regulation of leukocyte function in biological activities that promote inflammation, such as in periodontitis. A systematic review and meta-analysis was conducted with the primary objective of investigating the roles of MCP-1 in the gingival crevicular fluid (GCF) of subjects with chronic periodontitis compared to periodontally healthy subjects. The study protocol adhered to PRISMA guidelines.
View Article and Find Full Text PDFIntroduction: Artificial intelligence (AI) has emerged as a revolutionary technology with diverse applications across various domains, orthodontics included. This review article explores the widespread applications of AI in orthodontics and discusses the advantages and potential implications of AI in this specialized domain. The use of AI algorithms and machine learning techniques has shown promise in enhancing orthodontic diagnosis, automating cephalometric tracing, estimating growth and development, assessing facial proportions, aiding in orthodontic treatment planning, guiding decisions on orthognathic surgery, and facilitating image segmentation and landmark identification.
View Article and Find Full Text PDFThe addition of zinc oxide (ZnO) to mineral trioxide aggregate (MTA) has been shown to prevent tooth discoloration; however, its biological effects remain unclear. This study aimed to evaluate the pulpal responses to MTA containing 5% ZnO in full pulpotomy of dogs' teeth. Forty caries-free premolars from mixed-breed dogs were subjected to full pulpotomy.
View Article and Find Full Text PDFClin Med Insights Case Rep
April 2025
Age-related macular degeneration (AMD) is a leading cause of significant vision impairment in individuals aged 50 and older, primarily impacting central vision. This study seeks to investigate potential associations between periodontal disease and age-related maculopathy in the analyzed clinical case. A male subject of 66 years old, with age-related degenerative maculopathy and severe periodontal disease, was evaluated and treated.
View Article and Find Full Text PDFJ Appl Biomater Funct Mater
April 2025
Objective: The aim of this systematic review was to investigate, identify, and summarize the existing literature on the levels of proinflammatory cytokines and chemokines present in gingival crevicular fluid (GCF) of primary teeth restored with stainless steel crowns (SSC) versus control teeth.
Materials And Methods: The systematic review was registered in the Open Science Framework (ID): 10.17605/OSF.
Background And Objective: Proinflammatory cytokines and enzymes responsible for tissue destruction are important in the development of periodontitis. This study compared salivary concentrations of interleukin-1 beta (IL-1β), matrix metalloproteinases (MMP-8), and (MMP-9) in individuals with and without periodontitis to evaluate their diagnostic utility as potential biomarkers.
Materials And Methods: A comprehensive search was performed across PubMed, Scopus, ScienceDirect, and Google Scholar, supplemented by manual searches in relevant journals up to January 2024.
J Appl Biomater Funct Mater
April 2025
Bruxism affects millions worldwide, leading to dental damage like worn teeth and tooth loss. Resin 3D printing presents a promising method for creating intricate, comfortable, and durable occlusal splints. This study examines how printing parameters-layer thickness, orientation angle, and curing time-affect the mechanical (compressive strength, wear rate, impact strength) and physical (water sorption, surface roughness, dimensional accuracy) properties of occlusal splints made from a methacrylate-based resin.
View Article and Find Full Text PDFBackground: All patients deserve quality care, regardless of their cultural, ethnic, or linguistic backgrounds. In Pakistan's diverse society, cultural competence in dentistry is crucial for patient-centered care. This study assesses and compares cultural competence levels between dental house officers (DHOs) and general dentists (GDs).
View Article and Find Full Text PDFBackground: Titanium is commonly used for dental implants due to its high biocompatibility and durability. However, concerns about metal ion release and aesthetic limitations in certain tissue biotypes have driven the search for alternative materials. Polyetherketoneketone (PEKK), a high-performance polymer, has emerged as a promising option due to its biomimetic properties.
View Article and Find Full Text PDFArch Oral Biol
July 2025
Objectives: This systematic review aimed to explore the role of Azurocidin (Azu) in the pathogenesis of periodontal and peri-implant disease and its potential use as an inflammatory biomarker.
Materials And Methods: Four electronic databases were used for study identification: PubMed, Google Scholar, ScienceDirect, and Scopus from Oct 10, 1991 to Jul 15, 2024. Study selection and data extraction were performed in a blinded and independent manner.
Objective: This study aimed to evaluate the influence of scanning speed and distance on the precision and quality of digital intraoral scans.
Data: The PICO strategy was employed to delineate the inclusion and exclusion criteria. The acquired records underwent filtration according to eligibility criteria, with essential information subsequently extracted.
Background: Maxillofacial materials have been developed to provide natural and long-lasting prosthetic solutions for patients with facial anomalies caused by trauma, surgery, or congenital diseases. The durability and lifespan of maxillofacial silicone materials are important factors to consider in prosthetic rehabilitation. The tear strength of these materials is a crucial characteristic that directly affects their ability to withstand wear, tear, and deformation over time.
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