Microscope-assisted, rodent whole heart perfusion fixation for histological characterization of myocardium remodeling.

Investigating mechanisms of heart disease, its progression, and developing therapeutics that target cardiac remodeling often requires translational model organisms. rodent models have been well established as a means to explore heart pathologies for their physiologic similarities, low cost, reproducibility, and breeding efficiency. Chemical fixation and harvest of cardiovascular structures is an essential preliminary step to histological assessment that enables the characterization of macro and subtle tissue changes.

Quantitative and Qualitative Symmetry Analysis of Open Reduction and Fixation of Zygomatic Complex Fractures.

Zygomatic complex (ZMC) fractures are among the most common craniofacial injuries, impacting both function and esthetics. This study evaluates the effectiveness of open reduction and internal fixation (ORIF) in restoring facial symmetry following ZMC fractures. Sixteen patients with unilateral ZMC fractures underwent a retrospective analysis comparing preoperative and postoperative computed tomography (CT) scans to a control group of ten individuals without facial fractures.

Cognitive assessment of nursing home residents: Survey data on tools used and perceptions of use among social service professionals in one U.S. state.

Social service professionals routinely use screening tools to assess for cognitive decline or identify suspected dementia in nursing home residents. Published literature lacks details about the specific tools used and how professionals use and perceive them in practice. The aim of this study is to better understand cognitive screening roles performed by nursing home social service professionals and how they view their use and efficacy.

The Impact of Trauma-Informed Training for a Youth Residential Center on Staff Attitudes and Behavior.

Purpose: Children with behavioral issues in residential care settings have high rates of trauma, with a range of trauma experiences such as abuse and neglect, issues with attachment, and multiple disruptions in placements. Staff in these settings should have an understanding of trauma, its impact, and how to engage in trauma-informed practice.

Unlabelled: The purpose of this study was to examine whether a trauma-informed training, developed specifically based on the identified needs of a residential group care facility, had an impact on future staff attitudes and behaviors.

Global drivers of mangrove loss in protected areas.

Despite increasing efforts and investment in mangrove conservation, mangrove cover continues to decline globally. The extent to which protected area (PA) management effectively prevents mangrove loss globally across differing management objectives and governance types is not well understood. We combined remote sensing data with PA information to identify the extent and the drivers of mangrove loss across PAs with distinct governance types and protection levels based on categories developed by the International Union for Conservation of Nature (IUCN).

Optimal fusion of genotype and drug embeddings in predicting cancer drug response.

Predicting cancer drug response using both genomics and drug features has shown some success compared to using genomics features alone. However, there has been limited research done on how best to combine or fuse the two types of features. Using a visible neural network with two deep learning branches for genes and drug features as the base architecture, we experimented with different fusion functions and fusion points.

Educating Trainees to Treat Peripheral Arterial Disease: Challenges and Opportunities.

Educating trainees to treat Peripheral Artery Disease (PAD) carries specific contemporary challenges. The national increase of the prevalence of PAD combined with a significant shortage of vascular surgeons creates a need for concern for future management of this complex disease. Over the past 2 decades, traditional (5 + 2) and integrated (0 + 5) paradigms have fostered trainee annual growth and comparable case distribution and volumes in endovascular and open surgical treatment options have been maintained.

Global hotspots of salt marsh change and carbon emissions.

Salt marshes provide ecosystem services such as carbon sequestration, coastal protection, sea-level-rise (SLR) adaptation and recreation. SLR, storm events, drainage and mangrove encroachment are known drivers of salt marsh loss. However, the global magnitude and location of changes in salt marsh extent remains uncertain.

Health programming priorities among faith communities in Jefferson County, Alabama.

This paper details findings from interviews with 32 faith leaders regarding their interest in and preferences for collaborative health partnerships with an academic center. Participants were willing to partner to develop equitable, sustainable, and trust-based relationships for the purpose of meeting the health needs of their congregations. We also describe the planning and early development of faith community-academic partnership focused on providing information and resources aimed at improving health.

Salt marsh monitoring along the mid-Atlantic coast by Google Earth Engine enabled time series.

Salt marshes provide a bulwark against sea-level rise (SLR), an interface between aquatic and terrestrial habitats, important nursery grounds for many species, a buffer against extreme storm impacts, and vast blue carbon repositories. However, salt marshes are at risk of loss from a variety of stressors such as SLR, nutrient enrichment, sediment deficits, herbivory, and anthropogenic disturbances. Determining the dynamics of salt marsh change with remote sensing requires high temporal resolution due to the spectral variability caused by disturbance, tides, and seasonality.

Fertility Intentions and Perspectives on Contraceptive Involvement Among Low-Income Men Aged 25 to 55.

Context: Unintended pregnancy is disproportionately reported by low-income individuals in the United States, and studies of men's roles in preventing pregnancy have largely focused on adolescents and young adults. Less is known about the pregnancy-related attitudes and behaviors among men older than 24, who are involved in the majority of pregnancies ending in a birth.

Methods: Between December 2015 and August 2016, in-depth interviews were conducted with 26 low-income men in Alabama who were aged 25-55, were sexually active and did not want more children.

Do income inequalities in higher weight status depend on social integration?

Those with higher incomes tend to have better health outcomes, including healthy weight status. We use data from the 2003-2008 National Health and Nutrition Examination Survey (NHANES) to examine whether the association between higher weight status and social integration varies by income. We examine gender differences in weight status, measured by BMI and obesity, by social integration and income, and find evidence that high social integration is a risk factor for higher weight status among low-income men.

The importance of the biliopancreatic limb length in gastric bypass: A systematic review.

Background: Bariatric surgery has proven to be the most durable treatment for obesity, and it also provides improvement of obesity's associated co-morbidities. Although several mechanisms for its metabolic effects have been studied, the implications of the surgically constructed anatomy on its functioning physiology have not been elucidated. This leaves some uncertainty regarding the recommended limb lengths in Roux-en-Y gastric bypass.

Evaluation of riparian condition of Songhua River by integration of remote sensing and field measurements.

Riparian zone is crucial to the health of streams and their surrounding environment. Evaluation of riparian condition is essential to achieve and maintain good stream health, as well as to sustain ecological functions that riparian areas provide. This manuscript is aimed to evaluate riparian conditions of Songhua River, the fifth longest river in China, using physical structural integrality (PSI) values derived from remote sensing and validated by field measurements.

Barriers to Offering Vasectomy at Publicly Funded Family Planning Organizations in Texas.

Few publicly funded family planning clinics in the United States offer vasectomy, but little is known about the reasons this method is not more widely available at these sources of care. Between February 2012 and February 2015, three waves of in-depth interviews were conducted with program administrators at 54 family planning organizations in Texas. Participants described their organization's vasectomy service model and factors that influenced how frequently vasectomy was provided.

Meals Enhancing Nutrition After Discharge: Findings from a Pilot Randomized Controlled Trial.

Background: After older adults experience episodes of poor health or are hospitalized, they may not return to premorbid or prehospitalization eating behaviors. Furthermore, poor nutrition increases hospital readmission risk, but evidence-based interventions addressing these risks are limited.

Objective: This pilot study's objective was to evaluate the feasibility of conducting a randomized controlled trial assessing a post-discharge home-delivered meal program's impact on older adults' nutritional intake and hospital readmissions and to assess patient acceptability and satisfaction with the program.

Does Participation in Home-Delivered Meals Programs Improve Outcomes for Older Adults? Results of a Systematic Review.

Participation in home-delivered meals programs may contribute to the health and independence of older adults living in the community, especially those who are food insecure or those who are making transitions from acute, subacute, and chronic care settings to the home. The purpose of this study was to conduct a comprehensive and systematic review of all studies related to home-delivered meals in order to shed light on the state of the science. A complete review of articles appearing in PubMed using the keyword "Meal" was conducted; and titles, abstracts, and full-texts were screened for relevance.

Peer-assisted bedside teaching rounds.

Background: Although postgraduate trainees play a well-accepted role in medical education, little consideration has traditionally been given to senior undergraduate trainees as teachers. Recently, research has shown senior medical students (SMS) can play an effective teaching role for junior medical students (JMS) in non-clinical medical settings.

Purpose: The purpose of our study was to understand the perceptions of SMSs as teachers in a clinical environment for JMS.

Black megachurch websites: an assessment of health content for congregations and communities.

This study examines the health-related content of Black megachurch websites in the southeastern United States. Data collection resulted in the identification of qualitative themes and frequencies of references to general health, specific health conditions, and corresponding general and specific health ministries. The most salient qualitative themes included holistic definitions of health, attention to racial health disparities, belief in divine health and protection from illness, emphasis on individual health responsibility, and belief in a religion-health connection.

An endogenous green fluorescent protein-photoprotein pair in Clytia hemisphaerica eggs shows co-targeting to mitochondria and efficient bioluminescence energy transfer.

Green fluorescent proteins (GFPs) and calcium-activated photoproteins of the aequorin/clytin family, now widely used as research tools, were originally isolated from the hydrozoan jellyfish Aequora victoria. It is known that bioluminescence resonance energy transfer (BRET) is possible between these proteins to generate flashes of green light, but the native function and significance of this phenomenon is unclear. Using the hydrozoan Clytia hemisphaerica, we characterized differential expression of three clytin and four GFP genes in distinct tissues at larva, medusa and polyp stages, corresponding to the major in vivo sites of bioluminescence (medusa tentacles and eggs) and fluorescence (these sites plus medusa manubrium, gonad and larval ectoderms).