Somatic symptom disorder was common in children and adolescents attending an emergency department complaining of pain.

Aim: The aim of this study was to quantify the prevalence of somatic pain in a paediatric emergency department (ED).

Methods: We conducted a prospective observational study using patients admitted to the ED of an Italian children's hospital between December 2014 and February 2015. We enrolled children aged 7-17 who turned up at the ED complaining of pain.

A red baby should not be taken too lightly.

Aim: To identify clinical and laboratory features that can drive the differential diagnosis of a primary immunodeficiency diseases in patients with ectodermal defects.

Methods: Analysis of selected teaching cases.

Results: We identified four exemplary cases that allowed to point out specific clues.

The universe of immune deficiencies in Crohn's disease: a new viewpoint for an old disease?

Crohn's disease (CD) is generally considered a multifactorial disorder, since different genetic and environmental factors are thought to play a role in its pathogenesis. Recently, genome wide linkage studies allowed to identify the association of several loci with the increased risk of CD, although it is still unclear how they interact with environmental factors in causing the disease. The fact that many CD-risk-related genes are involved in the function of phagocytes seems in agreement with the well known role of these cells in CD histopathology.