Somatostatin and dopamine receptor expression in neuroendocrine neoplasms: correlation of immunohistochemical findings with somatostatin receptor scintigraphy visual scores.

Context: The expression of somatostatin (sstr1-5) and dopamine (DR) receptors in neuroendocrine neoplasms (NENs) facilitates diagnosis by tumour visualization with somatostatin receptor scintigraphy (SRS) and directs towards specific treatment with peptide receptor radionuclide therapy (PRRT) with radiolabelled somatostatin analogues.

Objective: To investigate the co-expression of sstrs, D2R in relation to pre-operative SRSs in NENs.

Design: Prospective two-centre study.

Etiology of anemia in patients with advanced heart failure.

Objectives: We prospectively investigated the causes of anemia in patients with advanced congestive heart failure (CHF).

Background: Anemia is common in patients with advanced CHF, and its etiology is generally considered to be multifactorial. However, despite its importance, precise information is lacking regarding the prevalence of putative etiologic factors.