Publications by authors named "Evanthia Diakatou"

Context: The expression of somatostatin (sstr1-5) and dopamine (DR) receptors in neuroendocrine neoplasms (NENs) facilitates diagnosis by tumour visualization with somatostatin receptor scintigraphy (SRS) and directs towards specific treatment with peptide receptor radionuclide therapy (PRRT) with radiolabelled somatostatin analogues.

Objective: To investigate the co-expression of sstrs, D2R in relation to pre-operative SRSs in NENs.

Design: Prospective two-centre study.

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Background: Endoscopic ultrasound staging and guided fine needle aspiration biopsy (EUS-FNA) is a highly accurate diagnostic method, useful in characterizing pancreatic lesions, obtaining definitive tissue diagnosis in patients with suspected pancreatic lesions, and providing accurate locoregional staging that enhances diagnostic certainty and evaluation of appropriateness of surgical intervention. The aims of this study were to evaluate the preoperative contribution of EUS staging and EUS-FNA in patients with suspected resectable pancreatic malignancies.

Patients And Methods: A prospective study was conducted in a tertiary referral center.

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Primary lymphomas of the spermatic cord are extremely rare. To date, only 15 cases have been reported in the international literature. Herein, we report a new case of a primary lymphoma of the spermatic cord.

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Article Synopsis
  • Somatostatin and its analogs interact with five specific receptors (sstr1-5) found on endocrine tumors, while dopamine operates through five receptors (D1R-D5R), which have also been discovered in these tumors.
  • In a study of gastroenteropancreatic neuroendocrine tumors (GEP-NETs), various tumor types were examined, revealing that 76.31% showed positive expression for somatostatin receptors, with sstr2A being the most common.
  • The finding of high sstr2A and sstr2B expression suggests that these receptors could improve imaging and targeted therapy for GEP-NETs, and their co-expression with dopamine receptor D2R provides potential new treatment
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